Gramicidin
From Proteopedia
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| - | <Structure load='2xds' size='350' scene= caption='Gramicidin D dimer with formyl-valine, formyl-isoleucine complex with PEG 1500 and ethanolamine , [[2xdc]]'/> | + | <Structure load='2xds' size='350' side=right scene= caption='Gramicidin D dimer with formyl-valine, formyl-isoleucine complex with PEG 1500 and ethanolamine , [[2xdc]]'/> |
| - | + | == Function == | |
| - | [[Gramicidin]] (GCDN) is a polypeptide composed of alternating L- and D-amino acids | + | [[Gramicidin]] (GCDN) is a polypeptide composed of alternating L- and D-amino acids. It is produced by the bacteria ''Bacillus brevis''<ref>PMID:5288776</ref>.<br /> |
* '''GCDN S''' is an antibiotic cyclic polypeptide.<br /> | * '''GCDN S''' is an antibiotic cyclic polypeptide.<br /> | ||
* '''GCDN D''' is a mixture of GCDN A, B, C. <br /> | * '''GCDN D''' is a mixture of GCDN A, B, C. <br /> | ||
See theoretical model of [[Gramicidin Channel in Lipid Bilayer]]. | See theoretical model of [[Gramicidin Channel in Lipid Bilayer]]. | ||
| + | ==Relevance == | ||
| + | GCDN has bactericidal activity and is used as a topical antibiotic and as topical contraceptive<ref>PMID:8836773</ref>. | ||
== 3D Structures of Gramicidin == | == 3D Structures of Gramicidin == | ||
Revision as of 08:44, 16 March 2016
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Function
Gramicidin (GCDN) is a polypeptide composed of alternating L- and D-amino acids. It is produced by the bacteria Bacillus brevis[1].
- GCDN S is an antibiotic cyclic polypeptide.
- GCDN D is a mixture of GCDN A, B, C.
See theoretical model of Gramicidin Channel in Lipid Bilayer.
Relevance
GCDN has bactericidal activity and is used as a topical antibiotic and as topical contraceptive[2].
3D Structures of Gramicidin
Updated on 16-March-2016
