Horseradish peroxidase
From Proteopedia
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| - | {{STRUCTURE_6atj| PDB=6atj | SIZE=400| SCENE= |right| CAPTION=Horseradish peroxidase containing heme group complex with ferulic acid and Ca+2 ion (green), [[6atj]] }} | ||
| + | <StructureSection load='2atj' size='350' side='right' caption='Horseradish peroxidase containing heme group complex with ferulic acid and Ca+2 ion (green) (PDB entry [[2pm4]])' scene=''> | ||
== Function == | == Function == | ||
'''Horseradish peroxidase''' (HRP) catalyzes the oxidation of luminol to 3-aminophthalate using hydrogen peroxide. The reaction is accompanied by emission of light. In the presence of chemicals, particularly – p-iodophenol, the light emission is enhanced 1000-fold. Upon addition of the proper substrate, the HRP complex emits colored light. HRP contains a heme group<ref>PMID:14751298</ref>. | '''Horseradish peroxidase''' (HRP) catalyzes the oxidation of luminol to 3-aminophthalate using hydrogen peroxide. The reaction is accompanied by emission of light. In the presence of chemicals, particularly – p-iodophenol, the light emission is enhanced 1000-fold. Upon addition of the proper substrate, the HRP complex emits colored light. HRP contains a heme group<ref>PMID:14751298</ref>. | ||
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== Relevance == | == Relevance == | ||
HRP isozyme C1a is widely used for detection of a labeled molecule to which it conjugates. | HRP isozyme C1a is widely used for detection of a labeled molecule to which it conjugates. | ||
| - | + | </StructureSection> | |
==3D structures of horseradish peroxidase== | ==3D structures of horseradish peroxidase== | ||
Revision as of 11:49, 24 March 2016
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3D structures of horseradish peroxidase
Updated on 24-March-2016
References
- ↑ Veitch NC. Horseradish peroxidase: a modern view of a classic enzyme. Phytochemistry. 2004 Feb;65(3):249-59. PMID:14751298
