Leukotriene A4 Hydrolase
From Proteopedia
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== Disease == | == Disease == | ||
Mutations in LTA4H are linked to susceptibility to asthma and to cardiovascular disease. | Mutations in LTA4H are linked to susceptibility to asthma and to cardiovascular disease. | ||
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| + | == Structural highlights == | ||
| + | LTA4H structure shows 3 domains: N-terminal, catalytic and C-terminal. The catalytic domain is made of 2 lobes: an α-helical one and an α/β one. The catalytic site is located between the 2 lobes and contains a Zn+2 ion<ref>PMID:11175901</ref> . | ||
== 3D Structures of Leukotriene A4 Hydrolase == | == 3D Structures of Leukotriene A4 Hydrolase == | ||
Revision as of 06:35, 13 April 2016
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