Sandbox WWC6

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'''Alpha-hemolysin''' [https://en.wikipedia.org/wiki/Hemolysin#.CE.B1-hemolysin] is a toxin secreted by Staphylococcus aureus as a pore-forming heptamer that binds to eukaryotic cell membranes. This protein belongs to a family of bacterial exotoxins[http://www.uniprot.org/uniprot/P09616]. The primary function of alpha-hemolysin is cytolytic, and is achieved by the release of cytosolic K<sup>+</sup> ions from the through the hydrophilic, transmembrane portion of the beta-barrel pore[http://www.sciencedirect.com/science/article/pii/S0041010101001532].
'''Alpha-hemolysin''' [https://en.wikipedia.org/wiki/Hemolysin#.CE.B1-hemolysin] is a toxin secreted by Staphylococcus aureus as a pore-forming heptamer that binds to eukaryotic cell membranes. This protein belongs to a family of bacterial exotoxins[http://www.uniprot.org/uniprot/P09616]. The primary function of alpha-hemolysin is cytolytic, and is achieved by the release of cytosolic K<sup>+</sup> ions from the through the hydrophilic, transmembrane portion of the beta-barrel pore[http://www.sciencedirect.com/science/article/pii/S0041010101001532].
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<applet load='1pgb' size='350' frame='true' align='right' caption='1pgb' scene='Insert optional scene name here' />
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<scene name='69/696302/Staphylococcal_alpha-hemolysin/1'>TextToBeDisplayed</scene>
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[[Image:MW_Folding_Simulations.gif]]
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<scene name='69/696302/N_to_c_rainbow/4'>N to C Sequence</scene>
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{{Template:ColorKey_Amino2CarboxyRainbow}}
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Let us color the two main forms of regular <scene name='69/696302/Secondary_structure/1'>Secondary Structure</scene> in this protein. {{Template:ColorKey_Helix}} appears in red, {{Template:ColorKey_Strand}} in yellow.
Let us color the two main forms of regular <scene name='69/696302/Secondary_structure/1'>Secondary Structure</scene> in this protein. {{Template:ColorKey_Helix}} appears in red, {{Template:ColorKey_Strand}} in yellow.

Revision as of 16:18, 16 April 2016

Function

Alpha-hemolysin [1] is a toxin secreted by Staphylococcus aureus as a pore-forming heptamer that binds to eukaryotic cell membranes. This protein belongs to a family of bacterial exotoxins[2]. The primary function of alpha-hemolysin is cytolytic, and is achieved by the release of cytosolic K+ ions from the through the hydrophilic, transmembrane portion of the beta-barrel pore[3].

Let us color the two main forms of regular in this protein. Alpha Helices appears in red,  Beta Strands  in yellow.


1. How many alpha helices are in this structure?

None.
One.
Four.

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