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'''Growth hormone releasing hormone''' (GHRH) is a secretory neurohormone that causes growth hormone to be released from the pituitary gland. It is naturally produced in the arcuate nucleus of the hypothalamus. The [[hormone]] is produced as a 44 amino acid peptide hormone, and first appears in the hypothalamus between 18 and 29 weeks of gestation, corresponding to the initial production of growth hormone by the fetus (Chawla 1983; Tuteja 2005)<ref>PMID:6344776</ref>. Growth hormone is required for normal fetal and post fetal development, including bone growth and the regulation of protein production and the metabolism of lipids and carbohydrates (Tang 2004)<ref>PMID:15525469</ref>. | '''Growth hormone releasing hormone''' (GHRH) is a secretory neurohormone that causes growth hormone to be released from the pituitary gland. It is naturally produced in the arcuate nucleus of the hypothalamus. The [[hormone]] is produced as a 44 amino acid peptide hormone, and first appears in the hypothalamus between 18 and 29 weeks of gestation, corresponding to the initial production of growth hormone by the fetus (Chawla 1983; Tuteja 2005)<ref>PMID:6344776</ref>. Growth hormone is required for normal fetal and post fetal development, including bone growth and the regulation of protein production and the metabolism of lipids and carbohydrates (Tang 2004)<ref>PMID:15525469</ref>. | ||
| - | <Structure load='Ghrh.pdb' size='350' frame='true' align='left' caption=' | + | <Structure load='Ghrh.pdb' size='350' frame='true' align='left' caption='Growth Hormone-Releasing Hormone, modelled using Phyre modelling engine.'> |
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 22:31, 27 April 2016
Introduction
Growth hormone releasing hormone (GHRH) is a secretory neurohormone that causes growth hormone to be released from the pituitary gland. It is naturally produced in the arcuate nucleus of the hypothalamus. The hormone is produced as a 44 amino acid peptide hormone, and first appears in the hypothalamus between 18 and 29 weeks of gestation, corresponding to the initial production of growth hormone by the fetus (Chawla 1983; Tuteja 2005)[1]. Growth hormone is required for normal fetal and post fetal development, including bone growth and the regulation of protein production and the metabolism of lipids and carbohydrates (Tang 2004)[2].
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