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Netrin receptor

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**[[4plo]] – mDCC fourth fibronectin type IV domain + neutrin-1 - mouse<BR />
**[[4plo]] – mDCC fourth fibronectin type IV domain + neutrin-1 - mouse<BR />
**[[3pzd]] – mDCC P3 motif + myosin-X <BR />
**[[3pzd]] – mDCC P3 motif + myosin-X <BR />
 +
**[[3laf]] – rDCC residues 39-421 - rat<BR />
*Netrin receptor UNC5A
*Netrin receptor UNC5A
**[[4v2a]] – hUNC5A ectodomain <BR />
**[[4v2a]] – hUNC5A ectodomain <BR />
 +
 +
*Netrin receptor UNC5B
 +
 +
**[[3g5b]] – rUNC5B cytoplasmic domain (mutant)<BR />
 +
 +
*Netrin receptor UNC5D
 +
 +
**[[4v2b]] – rUNC5D Ig1 domain <BR />
 +
**[[4v2c]] – rUNC5D Ig1 domain + FLRT2 LRR domain<BR />
 +
**[[5ftt]], [[5ftu]] – mUNC5D Ig1, Ig2, TSP1 domains + FLRT2 LRR domain + latrophilin 3<BR />
*Netrin receptor UNC5H2
*Netrin receptor UNC5H2

Revision as of 08:56, 8 May 2016

Glycosylated human netrin receptor DCC fibronectin type V-VI domains (green) complex with neutrin-1 (grey), sulfate, Ca+2 and Cl-1 ions (PDB code 4urt)

Drag the structure with the mouse to rotate

3D Structures of netrin receptor

Updated on 08-May-2016

References

  1. Moore SW, Tessier-Lavigne M, Kennedy TE. Netrins and their receptors. Adv Exp Med Biol. 2007;621:17-31. doi: 10.1007/978-0-387-76715-4_2. PMID:18269208 doi:http://dx.doi.org/10.1007/978-0-387-76715-4_2
  2. Mehlen P, Llambi F. Role of netrin-1 and netrin-1 dependence receptors in colorectal cancers. Br J Cancer. 2005 Jul 11;93(1):1-6. PMID:15956977 doi:http://dx.doi.org/10.1038/sj.bjc.6602656

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Michal Harel

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