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Neurexin

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{{STRUCTURE_3bod| PDB=3bod | SIZE=400| SCENE= |right|CAPTION=Mouse neurexin 1α LNS domain with Ca+2 ion ([[3bod]]) }}
{{STRUCTURE_3bod| PDB=3bod | SIZE=400| SCENE= |right|CAPTION=Mouse neurexin 1α LNS domain with Ca+2 ion ([[3bod]]) }}
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[[Neurexin|Neurexins]] (NRXN) are a family of presynaptic proteins which bind to the postsynaptic [[Neuroligin]] (NLGN) to form a complex which attaches neurons. The NRXN family contains 4 members which are numbered 1 to 4. The NRXN-α contains 6 homologous LNS domains while the NRXN-β contains only LNS6. See [[Neurodevelopmental Disorders]].
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[[Neurexin|Neurexins]] (NRXN) are a family of presynaptic proteins which bind to the postsynaptic [[Neuroligin]] (NLGN) to form a complex which attaches neurons. The NRXN family contains 4 members which are numbered 1 to 4<ref>PMID:12796785</ref>. The NRXN-α contains 6 homologous LNS domains while the NRXN-β contains only LNS6.
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For Structural Analysis of Neurexin, See: [[Neuroligin-Neurexin Interaction]]
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See: [[Neurodevelopmental Disorders]]<br />
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[[Neuroligin-Neurexin Interaction]]
== 3D Structures of Neurexin ==
== 3D Structures of Neurexin ==
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**[[3vkf]] - bNRXN-1β LNS domain+rNLGN-1 cholinesterase domain
**[[3vkf]] - bNRXN-1β LNS domain+rNLGN-1 cholinesterase domain
}}
}}
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== References ==
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<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 10:36, 8 May 2016

Template:STRUCTURE 3bod

Neurexins (NRXN) are a family of presynaptic proteins which bind to the postsynaptic Neuroligin (NLGN) to form a complex which attaches neurons. The NRXN family contains 4 members which are numbered 1 to 4[1]. The NRXN-α contains 6 homologous LNS domains while the NRXN-β contains only LNS6.

See: Neurodevelopmental Disorders
Neuroligin-Neurexin Interaction

3D Structures of Neurexin

08-May-2016

References

  1. ↑ Dean C, Scholl FG, Choih J, DeMaria S, Berger J, Isacoff E, Scheiffele P. Neurexin mediates the assembly of presynaptic terminals. Nat Neurosci. 2003 Jul;6(7):708-16. PMID:12796785 doi:http://dx.doi.org/10.1038/nn1074
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