Methanol dehydrogenase

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== Structural highlights ==
== Structural highlights ==
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PQQ and the hexa-coordinated Ca+2 are bound in a funnel-shaped internal cavity of MDH<ref>PMID:21356200</ref>.
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<scene name='49/490936/Cv/2'>PQQ and the hexa-coordinated Ca+2</scene> are bound in a <scene name='49/490936/Cv/5'>funnel-shaped internal cavity of MDH</scene><ref>PMID:21356200</ref>.
</StructureSection>
</StructureSection>
==3D structures of methanol dehydrogenase==
==3D structures of methanol dehydrogenase==

Revision as of 12:45, 8 May 2016

Methanol dehydrogenase large subunit (cyan and deeppink) and small subunit (green and yellow) complex with cofactor PQQ and Ca+2 ion (green), 2ad6

Drag the structure with the mouse to rotate

3D structures of methanol dehydrogenase

Updated on 08-May-2016

4aah, 1g72, 2ad6, 2ad7, 2ad8 – MmMDH α+β + Ca + PQQ – Methylophilus methylotrophus
1h4i, 1w6s - MeMDH α+β + Ca + PQQ – Methylobacterium extorquens
1h4j - MeMDH α (mutant) +β + Ca + PQQ
1lrw - MDH α+β + Ca + PQQ – Paracoccus denitrificans
2d0v - MDH α+β + Ca + PQQ – Hyphomicrobium denitrificans
4mae - MDH + Ce + PQQ – Methylacidiphilum fumariolicum
4tqo - MDH + Ca + PQQ – Methylococcus capsulatus

References

  1. ↑ Anthony C, Williams P. The structure and mechanism of methanol dehydrogenase. Biochim Biophys Acta. 2003 Apr 11;1647(1-2):18-23. PMID:12686102
  2. ↑ Li J, Gan JH, Mathews FS, Xia ZX. The enzymatic reaction-induced configuration change of the prosthetic group PQQ of methanol dehydrogenase. Biochem Biophys Res Commun. 2011 Mar 25;406(4):621-6. Epub 2011 Feb 26. PMID:21356200 doi:10.1016/j.bbrc.2011.02.107

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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