3roh
From Proteopedia
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<table><tr><td colspan='2'>[[3roh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_70 Staphylococcus aureus subsp. aureus 70]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ROH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ROH FirstGlance]. <br> | <table><tr><td colspan='2'>[[3roh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_70 Staphylococcus aureus subsp. aureus 70]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ROH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ROH FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr> | ||
- | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HMPREF0773_11197, lukE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=548475 Staphylococcus aureus subsp. aureus 70])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HMPREF0773_11197, lukE, lukEv, SAOUHSC_01955 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=548475 Staphylococcus aureus subsp. aureus 70])</td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3roh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3roh OCA], [http://pdbe.org/3roh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3roh RCSB], [http://www.ebi.ac.uk/pdbsum/3roh PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3roh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3roh OCA], [http://pdbe.org/3roh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3roh RCSB], [http://www.ebi.ac.uk/pdbsum/3roh PDBsum]</span></td></tr> | ||
</table> | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/LUKEV_STAA8 LUKEV_STAA8]] Part of a bi-component leucotoxin that acts by forming pores in the membrane of the target cells. The activity of LukEv-LukDv to rabbit leukocytes is similar to that of the Panton-Valentine leucocidin (PVL). LukEv-LukDv is hemolytic to rabbit red blood cells although the activity is only 8% of gamma-hemolysin.<ref>PMID:12636257</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == |
Revision as of 16:35, 10 May 2016
Crystal Structure of Leukotoxin (LukE) from Staphylococcus aureus subsp. aureus COL.
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Categories: Staphylococcus aureus subsp. aureus 70 | Anderson, W F | Bagnoli, F | Bottomley, M | Structural genomic | Dubrovska, I | Falugi, F | Grandi, G | Halavaty, A | Minasov, G | Shuvalova, L | Winsor, J | Csgid | Leukocidin | Leukocidin-like | Membrane and cell surface proteins and peptide | Pore-forming toxin | Toxin