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4y20

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'''Unreleased structure'''
 
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The entry 4y20 is ON HOLD until Paper Publication
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==Complex of human Galectin-1 and NeuAcalpha2-3Galbeta1-4Glc==
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<StructureSection load='4y20' size='340' side='right' caption='[[4y20]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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Authors: Lin, H.Y., Hsieh, T.J., Lin, C.H.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4y20]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y20 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y20 FirstGlance]. <br>
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Description: Complex of human Galectin-1 and NeuAcalpha2-3Galbeta1-4Glc
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SLT:5-(ACETYLAMINO)-3,5-DIDEOXYNON-2-ULOPYRANONOSYL-(2- 3)-BETA-D-LYXO-HEXOPYRANOSYL-(1- 4)HEXOPYRANOSE'>SLT</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
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[[Category: Hsieh, T.J]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4y1v|4y1v]], [[4y1u|4y1u]], [[4y1x|4y1x]], [[4y1y|4y1y]], [[4y1z|4y1z]], [[4y22|4y22]], [[4y24|4y24]], [[4y26|4y26]]</td></tr>
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[[Category: Lin, H.Y]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y20 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y20 OCA], [http://pdbe.org/4y20 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y20 RCSB], [http://www.ebi.ac.uk/pdbsum/4y20 PDBsum]</span></td></tr>
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[[Category: Lin, C.H]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/LEG1_HUMAN LEG1_HUMAN]] May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase.<ref>PMID:14617626</ref> <ref>PMID:18796645</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Hsieh, T J]]
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[[Category: Lin, C H]]
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[[Category: Lin, H Y]]
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[[Category: Complex]]
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[[Category: Galectin-1]]
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[[Category: Lectin]]
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[[Category: Neuacalpha2-3galbeta1-4glc]]
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[[Category: Sugar binding protein]]

Revision as of 04:02, 12 May 2016

Complex of human Galectin-1 and NeuAcalpha2-3Galbeta1-4Glc

4y20, resolution 2.20Å

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