Formate dehydrogenase

(Difference between revisions)

Revision as of 07:54, 7 June 2016

NAD-dependent formate dehydrogenase dimer complex with cofactor NAD and sulfate, 2nad

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-{{STRUCTURE_2nad|  PDB=2nad  | SIZE=400| SCENE= |right|CAPTION=NAD-dependent formate dehydrogenase dimer complex with cofactor NAD and sulfate,  [[2nad]]}}
+<StructureSection load='2nad' size='450' side='right' scene='' caption='NAD-dependent formate dehydrogenase dimer complex with cofactor NAD and sulfate,  [[2nad]]'>
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 '''Formate dehydrogenase''' (FDH) catalyzes the reversible two-electron oxidation of formate to bicarbonate.  The product electron is donated to either [[NAD]]+ in NAD-dependent FDH or to Mo-dependent FDH where the electron is donated to a Fe<sub>4</sub>S<sub>4</sub> center and then to cytochrome.  The '''Mo-dependent FDH-H''' from ''E. coli'' contains SelCys, Mo, molybdopterin guanosine dinucleotide (MGD) cofactor and Fe<sub>4</sub>S<sub>4</sub><ref>PMID:2094290</ref>.