Formate dehydrogenase
From Proteopedia
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| - | <StructureSection load='2nad' size='450' side='right' scene='' caption='NAD-dependent formate dehydrogenase dimer complex with cofactor NAD and sulfate, [[2nad]]'> | + | <StructureSection load='2nad' size='450' side='right' scene='49/491980/Cv/1' caption='NAD-dependent formate dehydrogenase dimer complex with cofactor NAD and sulfate, [[2nad]]'> |
'''Formate dehydrogenase''' (FDH) catalyzes the reversible two-electron oxidation of formate to bicarbonate. The product electron is donated to either [[NAD]]+ in NAD-dependent FDH or to Mo-dependent FDH where the electron is donated to a Fe<sub>4</sub>S<sub>4</sub> center and then to cytochrome. The '''Mo-dependent FDH-H''' from ''E. coli'' contains SelCys, Mo, molybdopterin guanosine dinucleotide (MGD) cofactor and Fe<sub>4</sub>S<sub>4</sub><ref>PMID:2094290</ref>. | '''Formate dehydrogenase''' (FDH) catalyzes the reversible two-electron oxidation of formate to bicarbonate. The product electron is donated to either [[NAD]]+ in NAD-dependent FDH or to Mo-dependent FDH where the electron is donated to a Fe<sub>4</sub>S<sub>4</sub> center and then to cytochrome. The '''Mo-dependent FDH-H''' from ''E. coli'' contains SelCys, Mo, molybdopterin guanosine dinucleotide (MGD) cofactor and Fe<sub>4</sub>S<sub>4</sub><ref>PMID:2094290</ref>. | ||
Revision as of 07:57, 7 June 2016
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3D structure of formate dehydrogenase
Updated on 07-June-2016
