Fructokinase

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{{STRUCTURE_3lki| PDB=3lki | SIZE=400| SCENE= |right|CAPTION=Se-Met fructokinase dimer complex with ATP (stick model), phosphate and K+ ion (purple), [[3lki]] }}
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<StructureSection load='3lki' size='450' side='right' scene='' caption='Se-Met fructokinase dimer complex with ATP (stick model), phosphate and K+ ion (purple), [[3lki]]'>
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== Function ==
== Function ==
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FRK deficiency in the liver causes the inherited metabolic disorder Fructosuria<ref>PMID:2992452</ref>.
FRK deficiency in the liver causes the inherited metabolic disorder Fructosuria<ref>PMID:2992452</ref>.
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</StructureSection>
==3D structures of fructokinase==
==3D structures of fructokinase==

Revision as of 12:32, 8 June 2016

Se-Met fructokinase dimer complex with ATP (stick model), phosphate and K+ ion (purple), 3lki

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3D structures of fructokinase

Updated on 08-June-2016

2qhp – FRK – Bacterioides thetaiotamicron
3ljs – XfFRK – Xylella fastidiosa
3hj6 – FRK – Halothermothrix orenii
3lki – XfFRK + ATP
3lm9 - BsFRK + ATP + fructose – Bacillus subtilis
3ohr - BsFRK + ADP
2v78, 2var – FRK – Sulfolobus solfataricus
3c8u – FRK – Silicibacter

References

  1. ↑ James HM, Williams SG, Bais R, Rofe AM, Edwards JB, Conyers RA. The metabolic production of oxalate from xylitol: activities of transketolase, transaldolase, fructokinase and aldolase in liver, kidney, brain, heart and muscle in the rat, mouse, guinea pig, rabbit and human. Int J Vitam Nutr Res Suppl. 1985;28:29-46. PMID:3009653
  2. ↑ Phillips MI, Davies DR. The mechanism of guanosine triphosphate depletion in the liver after a fructose load. The role of fructokinase. Biochem J. 1985 Jun 15;228(3):667-71. PMID:2992452

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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