Ornithine carbamoyltransferase
From Proteopedia
(Difference between revisions)
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== Function == | == Function == | ||
| - | '''Ornithine carbamoyltransferase''' (OTC) catalyzes the conversion of carbamoyl phosphate and ornithine to citrulline and phosphate. OTC is part of the arginine biosynthesis in plants and bacteria and part of the urea cycle in mammals. For details see [[Sanbox Reserved 684]]. | + | '''Ornithine carbamoyltransferase''' (OTC) catalyzes the conversion of carbamoyl phosphate and ornithine to citrulline and phosphate. OTC is part of the arginine biosynthesis in plants and bacteria and part of the urea cycle in mammals<ref>PMID:8845761</ref>. For details see [[Sanbox Reserved 684]]. |
== Disease == | == Disease == | ||
OCT deficiency is a genetic urea cycle disorder. | OCT deficiency is a genetic urea cycle disorder. | ||
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| + | == Structural highlights == | ||
==3D structures of ornithine carbamoyltransferase== | ==3D structures of ornithine carbamoyltransferase== | ||
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[[1duv]], [[2otc]] – EcOTC + ornithine derivative<br /> | [[1duv]], [[2otc]] – EcOTC + ornithine derivative<br /> | ||
[[1fb5]] – sOTC + norvaline - sheep<br /> | [[1fb5]] – sOTC + norvaline - sheep<br /> | ||
| + | == References == | ||
| + | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 09:29, 9 June 2016
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