This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5b5r

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "5b5r" [edit=sysop:move=sysop])
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 5b5r is ON HOLD
+
==Crystal structure of GSDMA3==
-
 
+
<StructureSection load='5b5r' size='340' side='right' caption='[[5b5r]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-
Authors:
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[5b5r]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B5R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5B5R FirstGlance]. <br>
-
Description:
+
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5b5r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b5r OCA], [http://pdbe.org/5b5r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5b5r RCSB], [http://www.ebi.ac.uk/pdbsum/5b5r PDBsum]</span></td></tr>
 +
</table>
 +
== Disease ==
 +
[[http://www.uniprot.org/uniprot/GSDA3_MOUSE GSDA3_MOUSE]] Defects in Gsdma3 are the cause of a number of alopecia phenotypes, bareskin (Bsk), defolliculated (Dfl), finnegan (Fgn) reduced coat 2 (Rco2), Rex-denuded (Re-den) and recombination induced mutation 3 (Rim3). These are dominant conditions characterized by loss of hair.<ref>PMID:15475261</ref> <ref>PMID:15737203</ref> <ref>PMID:17572385</ref>
 +
== Function ==
 +
[[http://www.uniprot.org/uniprot/GSDA3_MOUSE GSDA3_MOUSE]] Upon activation, mediates pyroptosis (PubMed:26375003). May play a role in the transition from catagen to telogen at the end of hair follicle morphogenesis (PubMed:15475261).<ref>PMID:15475261</ref> <ref>PMID:26375003</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Ding, J]]
 +
[[Category: Shao, F]]
 +
[[Category: Pyroptosis excutioner]]
 +
[[Category: Transport protein]]

Revision as of 22:21, 20 June 2016

Crystal structure of GSDMA3

5b5r, resolution 1.90Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5b5r"
Personal tools