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Pheromone binding protein
From Proteopedia
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<StructureSection load='3bfa' size='340' side='right' caption='Pheromone binding protein of honey bee complex with pheromone (PDB code [[3bfa]]).' scene=''> | <StructureSection load='3bfa' size='340' side='right' caption='Pheromone binding protein of honey bee complex with pheromone (PDB code [[3bfa]]).' scene=''> | ||
| - | Pheromone binding proteins [http://en.wikipedia.org/wiki/Pheromone_binding_protein (PBP)] are type of Odorant binding proteins [http://en.wikipedia.org/wiki/Odorant-binding_protein (OBP)] - soluble proteins mediating the early stages of volatiles detection in both insects and vertebrates<ref>DOI:10.3389/fphys.2014.00320</ref>. The volatiles (pheromones and other small hydrophobic molecules) are solubilized by the OBPs and activate the chemoreceptors. | + | __TOC__ |
| + | ==Introduction== | ||
| + | '''Pheromone binding proteins''' [http://en.wikipedia.org/wiki/Pheromone_binding_protein (PBP)] are type of Odorant binding proteins [http://en.wikipedia.org/wiki/Odorant-binding_protein (OBP)] - soluble proteins mediating the early stages of volatiles detection in both insects and vertebrates<ref>DOI:10.3389/fphys.2014.00320</ref>. The volatiles (pheromones and other small hydrophobic molecules) are solubilized by the OBPs and activate the chemoreceptors. | ||
As a model protein of this family we will further describe the well investigated Pheromone binding protein of the honey bee, ASP1. | As a model protein of this family we will further describe the well investigated Pheromone binding protein of the honey bee, ASP1. | ||
Revision as of 08:33, 23 June 2016
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3D structures of pheromone-binding protein
Updated on 23-June-2016
References
- ↑ Pelosi P, Iovinella I, Felicioli A, Dani FR. Soluble proteins of chemical communication: an overview across arthropods. Front Physiol. 2014 Aug 27;5:320. doi: 10.3389/fphys.2014.00320. eCollection, 2014. PMID:25221516 doi:http://dx.doi.org/10.3389/fphys.2014.00320
- ↑ Winston, M.L., 1987. The Biology of the Honey Bee. Harvard University Press, Cambridge, MA.
- ↑ Pesenti ME, Spinelli S, Bezirard V, Briand L, Pernollet JC, Tegoni M, Cambillau C. Structural basis of the honey bee PBP pheromone and pH-induced conformational change. J Mol Biol. 2008 Jun 27;380(1):158-69. Epub 2008 Apr 27. PMID:18508083 doi:10.1016/j.jmb.2008.04.048
