Phycocyanobilin:ferredoxin oxidoreductase
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_3i94| PDB=3i94 | SIZE=400| SCENE= |right|CAPTION=Phycocyanobilin:ferredoxin oxidoreductase complex with biliverdin and sulfate, [[3i94]] }} | {{STRUCTURE_3i94| PDB=3i94 | SIZE=400| SCENE= |right|CAPTION=Phycocyanobilin:ferredoxin oxidoreductase complex with biliverdin and sulfate, [[3i94]] }} | ||
| + | == Function == | ||
| + | '''Phycocyanobilin:ferredoxin oxidoreductase''' (PcyA) is a member of the Fd-dependent bilin family. PcyA reduces vinyl groups of biliverdin IX-α to yield phycocyanobilin<ref>PMID:15250720</ref>. Phycocyanobilin is a pigment precursor of the light-harvesting antennae in red algae and cyanobacteria. | ||
| - | '''Phycocyanobilin:ferredoxin oxidoreductase''' (PcyA) is a member of the Fd-dependent bilin family. PcyA reduces vinyl groups of biliverdin IX-α to yield phycocyanobilin. Phycocyanobilin is a pigment precursor of the light-harvesting antennae in red algae and cyanobacteria. | ||
| - | __NOTOC__ | ||
== 3D Structures of Phycocyanobilin:ferredoxin oxidoreductase== | == 3D Structures of Phycocyanobilin:ferredoxin oxidoreductase== | ||
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[[3f0l]], [[3fom]], [[3nb8]], [[3nb9]] – SyPcyA (mutant)<br /> | [[3f0l]], [[3fom]], [[3nb8]], [[3nb9]] – SyPcyA (mutant)<br /> | ||
[[3i8u]] – SyPcyA + biliverdin derivative | [[3i8u]] – SyPcyA + biliverdin derivative | ||
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| + | == References == | ||
| + | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 10:28, 3 July 2016
Function
Phycocyanobilin:ferredoxin oxidoreductase (PcyA) is a member of the Fd-dependent bilin family. PcyA reduces vinyl groups of biliverdin IX-α to yield phycocyanobilin[1]. Phycocyanobilin is a pigment precursor of the light-harvesting antennae in red algae and cyanobacteria.
3D Structures of Phycocyanobilin:ferredoxin oxidoreductase
3ajg, 3i95 – SyPcyA (mutant) + biliverdin IX – Synechocystis
3ajh – SyPcyA (mutant) + biliverdin XIII
3i94 - SyPcyA + biliverdin XIII
3f0l, 3fom, 3nb8, 3nb9 – SyPcyA (mutant)
3i8u – SyPcyA + biliverdin derivative
References
- ↑ Tu SL, Gunn A, Toney MD, Britt RD, Lagarias JC. Biliverdin reduction by cyanobacterial phycocyanobilin:ferredoxin oxidoreductase (PcyA) proceeds via linear tetrapyrrole radical intermediates. J Am Chem Soc. 2004 Jul 21;126(28):8682-93. PMID:15250720 doi:http://dx.doi.org/10.1021/ja049280z
