Plasmid segregation protein ParM

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<StructureSection load='4a61' size='340' side='right' caption='plasmid segregation protein ParM complex with AMPPNP and Mg+2 ion (PDB code [[4a61]])' scene=''>
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<StructureSection load='4a61' size='340' side='right' caption='plasmid segregation protein ParM complex with AMPPNP (stick model) and Mg+2 ion (green) (PDB code [[4a61]])' scene=''>
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'''Plasmid segregation protein''' (ParM) is required for plasmid partition and accurate segregation of low-copy-number plasmid R1. ParM polymerizes into double helical protofilaments with repeats similar to F-actin.
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== Function ==
== Function ==
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'''Plasmid segregation protein''' (ParM) is required for plasmid partition and accurate segregation of low-copy-number plasmid R1<ref>PMID:20844556</ref>.
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== Disease ==
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== Relevance ==
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== Structural highlights ==
== Structural highlights ==
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ParM polymerizes into double helical protofilaments with repeats similar to F-actin.

Revision as of 09:11, 4 July 2016

plasmid segregation protein ParM complex with AMPPNP (stick model) and Mg+2 ion (green) (PDB code 4a61)

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3D structures of plasmid segregation protein ParM

Updated on 04-July-2016

1mwk – ParM – Escherichias coli
1mwm – ParM + ADP
2zgy – ParM + GDP
2zgz – ParM + GMPPNP
4a61 – ParM + AMPPNP
5aey – ParM + AMPPNP - CryoEM
4a62 – ParM + ParR C terminus
2qu4, 2ghc, 3iku, 3iky, 4a6j, 5ai7 – ParM – CryoEM

References

  1. ↑ Salje J, Gayathri P, Lowe J. The ParMRC system: molecular mechanisms of plasmid segregation by actin-like filaments. Nat Rev Microbiol. 2010 Oct;8(10):683-92. doi: 10.1038/nrmicro2425. PMID:20844556 doi:http://dx.doi.org/10.1038/nrmicro2425

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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