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5eo7
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of AOL== | |
| + | <StructureSection load='5eo7' size='340' side='right' caption='[[5eo7]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5eo7]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EO7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EO7 FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SFU:METHYL+6-DEOXY-1-SELENO-ALPHA-L-GALACTOPYRANOSIDE'>SFU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5eo8|5eo8]]</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5eo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eo7 OCA], [http://pdbe.org/5eo7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5eo7 RCSB], [http://www.ebi.ac.uk/pdbsum/5eo7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5eo7 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The crystal structure of AOL (a fucose-specific lectin of Aspergillus oryzae) has been solved by SAD (single-wavelength anomalous diffraction) and MAD (multi-wavelength anomalous diffraction) phasing of seleno-fucosides. The overall structure is a six-bladed beta-propeller similar to that of other fucose-specific lectins. The fucose moieties of the seleno-fucosides are located in six fucose-binding sites. Although the Arg and Glu/Gln residues bound to the fucose moiety are common to all fucose-binding sites, the amino-acid residues involved in fucose binding at each site are not identical. The varying peak heights of the seleniums in the electron density map suggest that each fucose-binding site has a different carbohydrate binding affinity. | ||
| - | + | Six independent fucose-binding sites in the crystal structure of Aspergillus oryzae lectin.,Makyio H, Shimabukuro J, Suzuki T, Imamura A, Ishida H, Kiso M, Ando H, Kato R Biochem Biophys Res Commun. 2016 Jun 16. pii: S0006-291X(16)30987-1. doi:, 10.1016/j.bbrc.2016.06.069. PMID:27318092<ref>PMID:27318092</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| + | <div class="pdbe-citations 5eo7" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Ando, H]] | ||
| + | [[Category: Ishida, H]] | ||
| + | [[Category: Kato, R]] | ||
| + | [[Category: Kiso, M]] | ||
| + | [[Category: Makyio, H]] | ||
| + | [[Category: Shimabukuro, S]] | ||
| + | [[Category: Suzuki, T]] | ||
| + | [[Category: Aspergillus oryzae]] | ||
| + | [[Category: Lectin]] | ||
| + | [[Category: Phaing]] | ||
| + | [[Category: Seleno-fucose]] | ||
| + | [[Category: Sugar binding protein]] | ||
Revision as of 10:21, 13 July 2016
Crystal structure of AOL
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Categories: Ando, H | Ishida, H | Kato, R | Kiso, M | Makyio, H | Shimabukuro, S | Suzuki, T | Aspergillus oryzae | Lectin | Phaing | Seleno-fucose | Sugar binding protein
