This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5d0u
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| + | |||
==Crystal structure of the RNA-helicase Prp43 from Chaetomium thermophilum bound to ADP== | ==Crystal structure of the RNA-helicase Prp43 from Chaetomium thermophilum bound to ADP== | ||
<StructureSection load='5d0u' size='340' side='right' caption='[[5d0u]], [[Resolution|resolution]] 2.92Å' scene=''> | <StructureSection load='5d0u' size='340' side='right' caption='[[5d0u]], [[Resolution|resolution]] 2.92Å' scene=''> | ||
| Line 4: | Line 5: | ||
<table><tr><td colspan='2'>[[5d0u]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D0U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D0U FirstGlance]. <br> | <table><tr><td colspan='2'>[[5d0u]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D0U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D0U FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d0u OCA], [http://pdbe.org/5d0u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d0u RCSB], [http://www.ebi.ac.uk/pdbsum/5d0u PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d0u OCA], [http://pdbe.org/5d0u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d0u RCSB], [http://www.ebi.ac.uk/pdbsum/5d0u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5d0u ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | RNA helicases are indispensable for all organisms in each domain of life and have implications in numerous cellular processes. The DEAH-box RNA helicase Prp43 is involved in pre-mRNA splicing as well as rRNA maturation. Here, the crystal structure of Chaetomium thermophilum Prp43 at 2.9 A resolution is revealed. Furthermore, it is demonstrated that Prp43 from C. thermophilum is capable of functionally replacing its orthologue from Saccharomyces cerevisiae in spliceosomal disassembly assays. | ||
| + | |||
| + | Structural and functional analysis of the RNA helicase Prp43 from the thermophilic eukaryote Chaetomium thermophilum.,Tauchert MJ, Fourmann JB, Christian H, Luhrmann R, Ficner R Acta Crystallogr F Struct Biol Commun. 2016 Feb;72(Pt 2):112-20. doi:, 10.1107/S2053230X15024498. Epub 2016 Jan 22. PMID:26841761<ref>PMID:26841761</ref> | ||
| + | |||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 5d0u" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 08:07, 27 July 2016
Crystal structure of the RNA-helicase Prp43 from Chaetomium thermophilum bound to ADP
| |||||||||||
