4ewh
From Proteopedia
(Difference between revisions)
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==Co-crystal structure of ACK1 with inhibitor== | ==Co-crystal structure of ACK1 with inhibitor== | ||
<StructureSection load='4ewh' size='340' side='right' caption='[[4ewh]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='4ewh' size='340' side='right' caption='[[4ewh]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4ewh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[4ewh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EWH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EWH FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=T77:6-{4-[2-(DIMETHYLAMINO)ETHOXY]PHENYL}-N-(1,3-DITHIOLAN-2-YLMETHYL)-5-PHENYL-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE'>T77</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=T77:6-{4-[2-(DIMETHYLAMINO)ETHOXY]PHENYL}-N-(1,3-DITHIOLAN-2-YLMETHYL)-5-PHENYL-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE'>T77</scene></td></tr> | ||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TNK2, ACK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TNK2, ACK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ewh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ewh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ewh RCSB], [http://www.ebi.ac.uk/pdbsum/4ewh PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ewh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ewh OCA], [http://pdbe.org/4ewh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ewh RCSB], [http://www.ebi.ac.uk/pdbsum/4ewh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ewh ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4ewh" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Liu, J]] | [[Category: Liu, J]] | ||
[[Category: Walker, N]] | [[Category: Walker, N]] | ||
Revision as of 09:28, 4 August 2016
Co-crystal structure of ACK1 with inhibitor
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