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1kqf
From Proteopedia
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|PDB= 1kqf |SIZE=350|CAPTION= <scene name='initialview01'>1kqf</scene>, resolution 1.60Å | |PDB= 1kqf |SIZE=350|CAPTION= <scene name='initialview01'>1kqf</scene>, resolution 1.60Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand=6MO:MOLYBDENUM(VI)+ION'>6MO</scene>, <scene name='pdbligand= | + | |LIGAND= <scene name='pdbligand=6MO:MOLYBDENUM(VI)+ION'>6MO</scene>, <scene name='pdbligand=CDL:CARDIOLIPIN'>CDL</scene>, <scene name='pdbligand=CSE:SELENOCYSTEINE'>CSE</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MGD:2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE+GUANOSINE+DINUCLEOTIDE'>MGD</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene> |
| - | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Formate_dehydrogenase Formate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.2 1.2.1.2] </span> | |
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY=[[1kqg|1KQG]] | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kqf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kqf OCA], [http://www.ebi.ac.uk/pdbsum/1kqf PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1kqf RCSB]</span> | ||
}} | }} | ||
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[[Category: Jormakka, M.]] | [[Category: Jormakka, M.]] | ||
[[Category: Tornroth, S.]] | [[Category: Tornroth, S.]] | ||
| - | [[Category: 6MO]] | ||
| - | [[Category: CDL]] | ||
| - | [[Category: HEM]] | ||
| - | [[Category: MGD]] | ||
| - | [[Category: SF4]] | ||
[[Category: anaerobic]] | [[Category: anaerobic]] | ||
[[Category: dehydrogenase]] | [[Category: dehydrogenase]] | ||
| Line 48: | Line 46: | ||
[[Category: selenocysteine]] | [[Category: selenocysteine]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:52:08 2008'' |
Revision as of 18:52, 30 March 2008
| |||||||
| , resolution 1.60Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , , , , , | ||||||
| Activity: | Formate dehydrogenase, with EC number 1.2.1.2 | ||||||
| Related: | 1KQG
| ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
FORMATE DEHYDROGENASE N FROM E. COLI
Overview
The structure of the membrane protein formate dehydrogenase-N (Fdn-N), a major component of Escherichia coli nitrate respiration, has been determined at 1.6 angstroms. The structure demonstrates 11 redox centers, including molybdopterin-guanine dinucleotides, five [4Fe-4S] clusters, two heme b groups, and a menaquinone analog. These redox centers are aligned in a single chain, which extends almost 90 angstroms through the enzyme. The menaquinone reduction site associated with a possible proton pathway was also characterized. This structure provides critical insights into the proton motive force generation by redox loop, a common mechanism among a wide range of respiratory enzymes.
About this Structure
1KQF is a Protein complex structure of sequences from Escherichia coli. Full crystallographic information is available from OCA.
Reference
Molecular basis of proton motive force generation: structure of formate dehydrogenase-N., Jormakka M, Tornroth S, Byrne B, Iwata S, Science. 2002 Mar 8;295(5561):1863-8. PMID:11884747
Page seeded by OCA on Sun Mar 30 21:52:08 2008
Categories: Escherichia coli | Formate dehydrogenase | Protein complex | Byrne, B. | Iwata, S. | Jormakka, M. | Tornroth, S. | Anaerobic | Dehydrogenase | Fe4s4 | Formate | Integral membrane protein | Iron sulfur cluster | Mgd | Molybdenum | Molybdopterin | Molybdopterin guanine dinucleotide | Mpt | Oxidoreductase | Secy | Selenium | Selenocysteine
