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3mkl

From Proteopedia

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{{Seed}}
 
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[[Image:3mkl.jpg|left|200px]]
 
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==Crystal structure of DNA-binding transcriptional dual regulator from Escherichia coli K-12==
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The line below this paragraph, containing "STRUCTURE_3mkl", creates the "Structure Box" on the page.
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<StructureSection load='3mkl' size='340' side='right' caption='[[3mkl]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3mkl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MKL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MKL FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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-->
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gadX, yhiX, b3516, JW3484 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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{{STRUCTURE_3mkl| PDB=3mkl | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mkl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mkl OCA], [http://pdbe.org/3mkl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3mkl RCSB], [http://www.ebi.ac.uk/pdbsum/3mkl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3mkl ProSAT]</span></td></tr>
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</table>
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===Crystal structure of DNA-binding transcriptional dual regulator from Escherichia coli K-12===
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== Function ==
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[[http://www.uniprot.org/uniprot/GADX_ECOLI GADX_ECOLI]] Positively regulates the expression of about fifteen genes involved in acid resistance such as gadA, gadB and gadC. Depending on the conditions (growth phase and medium), can repress gadW.<ref>PMID:11298273</ref> <ref>PMID:11976288</ref> <ref>PMID:12446650</ref> <ref>PMID:12730179</ref> <ref>PMID:14617649</ref> <ref>PMID:14702398</ref>
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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3MKL is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MKL OCA].
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Check<jmol>
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[[Category: Escherichia coli]]
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<jmolCheckbox>
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[[Category: Chang, C.]]
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mk/3mkl_consurf.spt"</scriptWhenChecked>
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[[Category: Clancy, S.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Joachimiak, A.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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</jmolCheckbox>
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[[Category: Mack, J.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3mkl ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Ecoli]]
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[[Category: Chang, C]]
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[[Category: Clancy, S]]
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[[Category: Joachimiak, A]]
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[[Category: Structural genomic]]
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[[Category: Mack, J]]
[[Category: Dna-binding protein]]
[[Category: Dna-binding protein]]
[[Category: Mcsg]]
[[Category: Mcsg]]
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[[Category: Midwest center for structural genomic]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Protein structure initiative]]
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[[Category: Psi2]]
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[[Category: Structural genomic]]
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[[Category: Transcription regulator]]
[[Category: Transcription regulator]]
[[Category: Transcriptional dual regulator]]
[[Category: Transcriptional dual regulator]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 28 11:12:06 2010''
 

Current revision

Crystal structure of DNA-binding transcriptional dual regulator from Escherichia coli K-12

3mkl, resolution 2.15Å

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