This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3ma6
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | {{STRUCTURE_3ma6| PDB=3ma6 | SCENE= }} | ||
| - | ===Crystal structure of kinase domain of TgCDPK1 in presence of 3BrB-PP1=== | ||
| - | == | + | ==Crystal structure of kinase domain of TgCDPK1 in presence of 3BrB-PP1== |
| - | [[3ma6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <StructureSection load='3ma6' size='340' side='right' caption='[[3ma6]], [[Resolution|resolution]] 2.50Å' scene=''> |
| - | [[Category: | + | == Structural highlights == |
| - | [[Category: Amani, M | + | <table><tr><td colspan='2'>[[3ma6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Toxgo Toxgo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MA6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MA6 FirstGlance]. <br> |
| - | [[Category: Arrowsmith, C H | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DXR:3-(3-BROMOBENZYL)-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE'>DXR</scene></td></tr> |
| - | [[Category: Artz, J D | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CDPK1, TGME49_101440 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5811 TOXGO])</td></tr> |
| - | [[Category: Bochkarev, A | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ma6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ma6 OCA], [http://pdbe.org/3ma6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ma6 RCSB], [http://www.ebi.ac.uk/pdbsum/3ma6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ma6 ProSAT]</span></td></tr> |
| - | [[Category: Bountra, C | + | </table> |
| - | [[Category: Edwards, A M | + | == Evolutionary Conservation == |
| - | [[Category: Hassani, A A | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [[Category: Hui, R | + | Check<jmol> |
| - | [[Category: Lin, Y H | + | <jmolCheckbox> |
| - | [[Category: Lourido, S | + | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ma/3ma6_consurf.spt"</scriptWhenChecked> |
| - | [[Category: Qiu, W | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | [[Category: | + | <text>to colour the structure by Evolutionary Conservation</text> |
| - | [[Category: Senisterra, G | + | </jmolCheckbox> |
| - | [[Category: Shokat, K | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ma6 ConSurf]. |
| - | [[Category: Sibley, L D | + | <div style="clear:both"></div> |
| - | [[Category: Vedadi, M | + | __TOC__ |
| - | [[Category: Weigelt, J | + | </StructureSection> |
| - | [[Category: Wernimont, A K | + | [[Category: Toxgo]] |
| - | [[Category: Zhang, C | + | [[Category: Amani, M]] |
| + | [[Category: Arrowsmith, C H]] | ||
| + | [[Category: Artz, J D]] | ||
| + | [[Category: Bochkarev, A]] | ||
| + | [[Category: Bountra, C]] | ||
| + | [[Category: Edwards, A M]] | ||
| + | [[Category: Hassani, A A]] | ||
| + | [[Category: Hui, R]] | ||
| + | [[Category: Lin, Y H]] | ||
| + | [[Category: Lourido, S]] | ||
| + | [[Category: Qiu, W]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Senisterra, G]] | ||
| + | [[Category: Shokat, K]] | ||
| + | [[Category: Sibley, L D]] | ||
| + | [[Category: Vedadi, M]] | ||
| + | [[Category: Weigelt, J]] | ||
| + | [[Category: Wernimont, A K]] | ||
| + | [[Category: Zhang, C]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Cdpk]] | [[Category: Cdpk]] | ||
| Line 31: | Line 47: | ||
[[Category: Serine/threonine-protein kinase]] | [[Category: Serine/threonine-protein kinase]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
| - | [[Category: Structural genomic]] | ||
| - | [[Category: Structural genomics consortium]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Current revision
Crystal structure of kinase domain of TgCDPK1 in presence of 3BrB-PP1
| |||||||||||
Categories: Toxgo | Amani, M | Arrowsmith, C H | Artz, J D | Bochkarev, A | Bountra, C | Edwards, A M | Hassani, A A | Hui, R | Lin, Y H | Lourido, S | Qiu, W | Structural genomic | Senisterra, G | Shokat, K | Sibley, L D | Vedadi, M | Weigelt, J | Wernimont, A K | Zhang, C | Atp-binding | Cdpk | Kinase | Nucleotide-binding | Parasitology | Serine/threonine-protein kinase | Sgc | Transferase
