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4ib4
From Proteopedia
(Difference between revisions)
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==Crystal structure of the chimeric protein of 5-HT2B-BRIL in complex with ergotamine== | ==Crystal structure of the chimeric protein of 5-HT2B-BRIL in complex with ergotamine== | ||
<StructureSection load='4ib4' size='340' side='right' caption='[[4ib4]], [[Resolution|resolution]] 2.70Å' scene=''> | <StructureSection load='4ib4' size='340' side='right' caption='[[4ib4]], [[Resolution|resolution]] 2.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4ib4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IB4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IB4 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4ib4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. The August 2013 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Serotonin Receptor'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2013_8 10.2210/rcsb_pdb/mom_2013_8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IB4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IB4 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=ERM:ERGOTAMINE'>ERM</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLB:(2S)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLB</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=ERM:ERGOTAMINE'>ERM</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLB:(2S)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLB</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">5HT2B_HUMAN, cybC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">5HT2B_HUMAN, cybC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ib4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ib4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ib4 RCSB], [http://www.ebi.ac.uk/pdbsum/4ib4 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ib4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ib4 OCA], [http://pdbe.org/4ib4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ib4 RCSB], [http://www.ebi.ac.uk/pdbsum/4ib4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ib4 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4ib4" style="background-color:#fffaf0;"></div> | ||
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| + | ==See Also== | ||
| + | *[[5-hydroxytryptamine receptor|5-hydroxytryptamine receptor]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Bacillus coli migula 1895]] | [[Category: Bacillus coli migula 1895]] | ||
| + | [[Category: RCSB PDB Molecule of the Month]] | ||
| + | [[Category: Serotonin Receptor]] | ||
[[Category: Cherezov, V]] | [[Category: Cherezov, V]] | ||
[[Category: Chu, M]] | [[Category: Chu, M]] | ||
Revision as of 18:21, 4 August 2016
Crystal structure of the chimeric protein of 5-HT2B-BRIL in complex with ergotamine
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Categories: Bacillus coli migula 1895 | RCSB PDB Molecule of the Month | Serotonin Receptor | Cherezov, V | Chu, M | GPCR, GPCR Network | Han, G W | Huang, X | Jiang, Y | Katritch, V | Liu, W | McCorvy, J D | Roth, B L | Siu, F Y | Stevens, R C | Vardy, E | Wacker, D | Wang, C | Xu, H E | Electron transport | Ergotamine | Gpcr | Gpcr dock | Gpcr network | Membrane protein | Novel protein engineering | Psi-biology | Signaling protein | Structural genomic
