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3ov1

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==Crystal Structure of the Grb2 SH2 Domain in Complex with a pYXN-Derived Tripeptide==
==Crystal Structure of the Grb2 SH2 Domain in Complex with a pYXN-Derived Tripeptide==
<StructureSection load='3ov1' size='340' side='right' caption='[[3ov1]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='3ov1' size='340' side='right' caption='[[3ov1]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ov1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OV1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OV1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ov1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OV1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OV1 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=1AC:1-AMINOCYCLOPROPANECARBOXYLIC+ACID'>1AC</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=1AC:1-AMINOCYCLOPROPANECARBOXYLIC+ACID'>1AC</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3s8l|3s8l]], [[3ove|3ove]], [[3ovf|3ovf]], [[3kfj|3kfj]], [[3imd|3imd]], [[3imj|3imj]], [[3in7|3in7]], [[3in8|3in8]], [[2h5k|2h5k]], [[3s8o|3s8o]], [[3s8n|3s8n]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3s8l|3s8l]], [[3ove|3ove]], [[3ovf|3ovf]], [[3kfj|3kfj]], [[3imd|3imd]], [[3imj|3imj]], [[3in7|3in7]], [[3in8|3in8]], [[2h5k|2h5k]], [[3s8o|3s8o]], [[3s8n|3s8n]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GRB2, ASH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GRB2, ASH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ov1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ov1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ov1 RCSB], [http://www.ebi.ac.uk/pdbsum/3ov1 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ov1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ov1 OCA], [http://pdbe.org/3ov1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ov1 RCSB], [http://www.ebi.ac.uk/pdbsum/3ov1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ov1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3ov1" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Human]]
[[Category: Clements, J H]]
[[Category: Clements, J H]]
[[Category: Martin, S F]]
[[Category: Martin, S F]]

Revision as of 19:19, 4 August 2016

Crystal Structure of the Grb2 SH2 Domain in Complex with a pYXN-Derived Tripeptide

3ov1, resolution 1.60Å

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