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4k0n

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==Crystal structure of human CLIC1 C24A mutant==
==Crystal structure of human CLIC1 C24A mutant==
<StructureSection load='4k0n' size='340' side='right' caption='[[4k0n]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
<StructureSection load='4k0n' size='340' side='right' caption='[[4k0n]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4jzq|4jzq]], [[4k0g|4k0g]], [[4k1d|4k1d]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4jzq|4jzq]], [[4k0g|4k0g]], [[4k1d|4k1d]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CLIC1, CLIC1 G6 NCC27, G6, NCC27 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CLIC1, CLIC1 G6 NCC27, G6, NCC27 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k0n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k0n RCSB], [http://www.ebi.ac.uk/pdbsum/4k0n PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k0n OCA], [http://pdbe.org/4k0n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4k0n RCSB], [http://www.ebi.ac.uk/pdbsum/4k0n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4k0n ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CLIC1_HUMAN CLIC1_HUMAN]] Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle.<ref>PMID:9139710</ref> <ref>PMID:10834939</ref> <ref>PMID:11195932</ref> <ref>PMID:11940526</ref> <ref>PMID:11978800</ref> <ref>PMID:11551966</ref> <ref>PMID:14613939</ref>
[[http://www.uniprot.org/uniprot/CLIC1_HUMAN CLIC1_HUMAN]] Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle.<ref>PMID:9139710</ref> <ref>PMID:10834939</ref> <ref>PMID:11195932</ref> <ref>PMID:11940526</ref> <ref>PMID:11978800</ref> <ref>PMID:11551966</ref> <ref>PMID:14613939</ref>
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==See Also==
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*[[Ion channels|Ion channels]]
== References ==
== References ==
<references/>
<references/>

Revision as of 19:45, 4 August 2016

Crystal structure of human CLIC1 C24A mutant

4k0n, resolution 1.25Å

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