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1ln4

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|ACTIVITY=
|ACTIVITY=
|GENE= YHBY ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
|GENE= YHBY ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
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|DOMAIN=
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ln4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ln4 OCA], [http://www.ebi.ac.uk/pdbsum/1ln4 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ln4 RCSB]</span>
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[[Category: Matthews, B W.]]
[[Category: Matthews, B W.]]
[[Category: Ostheimer, G J.]]
[[Category: Ostheimer, G J.]]
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[[Category: putative rna-binding protein; putative translation factor]]
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[[Category: putative rna-binding protein]]
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[[Category: putative translation factor]]
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Revision as of 19:04, 30 March 2008


PDB ID 1ln4

Drag the structure with the mouse to rotate
, resolution 1.5Å
Gene: YHBY (Escherichia coli)
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



CRYSTAL STRUCTURE OF E. COLI YHBY


Overview

E. coli YhbY belongs to a conserved family of hypothetical proteins represented in eubacteria, archaea, and plants (Pfam code UPF0044). Three maize proteins harboring UPF0044-like domains are required for chloroplast group II intron splicing, and bioinformatic data suggest a role for prokaryotic UPF0044 members in translation. The crystal structure of YhbY has been determined. YhbY has a fold similar to that of the C-terminal domain of translation initiation factor 3 (IF3C), which binds to 16S rRNA in the 30S ribosome. Modeling studies indicate that the same surface is highly basic in all members of UPF0044, suggesting a conserved RNA binding surface. Taken together, the evidence suggests that members of UPF0044 constitute a previously unrecognized class of RNA binding domain.

About this Structure

1LN4 is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Crystal structure of E. coli YhbY: a representative of a novel class of RNA binding proteins., Ostheimer GJ, Barkan A, Matthews BW, Structure. 2002 Nov;10(11):1593-601. PMID:12429100

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