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3i0a
From Proteopedia
(Difference between revisions)
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==Crystal structure of Siderocalin (NGAL, Lipocalin 2) K134A mutant complexed with Ferric Enterobactin== | ==Crystal structure of Siderocalin (NGAL, Lipocalin 2) K134A mutant complexed with Ferric Enterobactin== | ||
<StructureSection load='3i0a' size='340' side='right' caption='[[3i0a]], [[Resolution|resolution]] 2.60Å' scene=''> | <StructureSection load='3i0a' size='340' side='right' caption='[[3i0a]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3i0a]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3i0a]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I0A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3I0A FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2DS:N-[(2,3-DIHYDROXYPHENYL)CARBONYL]-O-[(2R)-2-{[(2,3-DIHYDROXYPHENYL)CARBONYL]AMINO}-3-HYDROXYPROPANOYL]-L-SERINE'>2DS</scene>, <scene name='pdbligand=3ET:O-[(2R)-2-AMINO-3-(D-SERYLOXY)PROPANOYL]-N-[(2,3-DIHYDROXYPHENYL)CARBONYL]-L-SERINE'>3ET</scene>, <scene name='pdbligand=DBH:2,3-DIHYDROXY-BENZOIC+ACID'>DBH</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MCJ:N-[(2,3-DIHYDROXYPHENYL)CARBONYL]-O-[(2S)-2-{[(2,3-DIHYDROXYPHENYL)CARBONYL]AMINO}-3-({N-[(2,3-DIHYDROXYPHENYL)CARBONYL]-L-SERYL}OXY)PROPANOYL]-D-SERINE'>MCJ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2DS:N-[(2,3-DIHYDROXYPHENYL)CARBONYL]-O-[(2R)-2-{[(2,3-DIHYDROXYPHENYL)CARBONYL]AMINO}-3-HYDROXYPROPANOYL]-L-SERINE'>2DS</scene>, <scene name='pdbligand=3ET:O-[(2R)-2-AMINO-3-(D-SERYLOXY)PROPANOYL]-N-[(2,3-DIHYDROXYPHENYL)CARBONYL]-L-SERINE'>3ET</scene>, <scene name='pdbligand=DBH:2,3-DIHYDROXY-BENZOIC+ACID'>DBH</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MCJ:N-[(2,3-DIHYDROXYPHENYL)CARBONYL]-O-[(2S)-2-{[(2,3-DIHYDROXYPHENYL)CARBONYL]AMINO}-3-({N-[(2,3-DIHYDROXYPHENYL)CARBONYL]-L-SERYL}OXY)PROPANOYL]-D-SERINE'>MCJ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3cmp|3cmp]], [[3hwd|3hwd]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3cmp|3cmp]], [[3hwd|3hwd]]</td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HNL, LCN2, NGAL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HNL, LCN2, NGAL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3i0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i0a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3i0a RCSB], [http://www.ebi.ac.uk/pdbsum/3i0a PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3i0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i0a OCA], [http://pdbe.org/3i0a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3i0a RCSB], [http://www.ebi.ac.uk/pdbsum/3i0a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3i0a ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3i0a ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Clifton, M C]] | [[Category: Clifton, M C]] | ||
[[Category: 25 kda alpha-2-microglobulin-related subunit of mmp-9]] | [[Category: 25 kda alpha-2-microglobulin-related subunit of mmp-9]] | ||
Revision as of 06:16, 5 August 2016
Crystal structure of Siderocalin (NGAL, Lipocalin 2) K134A mutant complexed with Ferric Enterobactin
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