This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4ai8
From Proteopedia
| Line 1: | Line 1: | ||
| + | |||
==FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH DAMINOZIDE== | ==FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH DAMINOZIDE== | ||
<StructureSection load='4ai8' size='340' side='right' caption='[[4ai8]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='4ai8' size='340' side='right' caption='[[4ai8]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4ai8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[4ai8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AI8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AI8 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DZA:DAMINOZIDE'>DZA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DZA:DAMINOZIDE'>DZA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wa4|2wa4]], [[2y0i|2y0i]], [[2w0x|2w0x]], [[2cgn|2cgn]], [[2wa3|2wa3]], [[2cgo|2cgo]], [[2yde|2yde]], [[1iz3|1iz3]], [[1h2m|1h2m]], [[1mze|1mze]], [[1mzf|1mzf]], [[2yc0|2yc0]], [[1yci|1yci]], [[1h2n|1h2n]], [[1h2k|1h2k]], [[2xum|2xum]], [[1h2l|1h2l]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wa4|2wa4]], [[2y0i|2y0i]], [[2w0x|2w0x]], [[2cgn|2cgn]], [[2wa3|2wa3]], [[2cgo|2cgo]], [[2yde|2yde]], [[1iz3|1iz3]], [[1h2m|1h2m]], [[1mze|1mze]], [[1mzf|1mzf]], [[2yc0|2yc0]], [[1yci|1yci]], [[1h2n|1h2n]], [[1h2k|1h2k]], [[2xum|2xum]], [[1h2l|1h2l]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide-aspartate_beta-dioxygenase Peptide-aspartate beta-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.11.16 1.14.11.16] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide-aspartate_beta-dioxygenase Peptide-aspartate beta-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.11.16 1.14.11.16] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ai8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ai8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ai8 RCSB], [http://www.ebi.ac.uk/pdbsum/4ai8 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ai8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ai8 OCA], [http://pdbe.org/4ai8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ai8 RCSB], [http://www.ebi.ac.uk/pdbsum/4ai8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ai8 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| Line 18: | Line 19: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4ai8" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
| Line 25: | Line 27: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Peptide-aspartate beta-dioxygenase]] | [[Category: Peptide-aspartate beta-dioxygenase]] | ||
[[Category: Chowdhury, R]] | [[Category: Chowdhury, R]] | ||
Revision as of 11:20, 5 August 2016
FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH DAMINOZIDE
| |||||||||||
Categories: Human | Peptide-aspartate beta-dioxygenase | Chowdhury, R | Clifton, I J | Kawamura, A | King, O N.F | Mcdonough, M A | Rose, N R | Schofield, C J | Ankyrin repeat domain | Beta-hydroxylation | Dioxygenase | Dsbh | Facial triad | Helix-loop-helix-beta | Metal-binding | Oxidoreductase | Transcription activator/inhibitor | Transcription and epigenetic regulation
