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3o46
From Proteopedia
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| - | {{STRUCTURE_3o46| PDB=3o46 | SCENE= }} | ||
| - | ===Crystal structure of the PDZ domain of MPP7=== | ||
| - | ==Function== | + | ==Crystal structure of the PDZ domain of MPP7== |
| + | <StructureSection load='3o46' size='340' side='right' caption='[[3o46]], [[Resolution|resolution]] 1.30Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3o46]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O46 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3O46 FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | ||
| + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MPP7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o46 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o46 OCA], [http://pdbe.org/3o46 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3o46 RCSB], [http://www.ebi.ac.uk/pdbsum/3o46 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3o46 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
[[http://www.uniprot.org/uniprot/MPP7_HUMAN MPP7_HUMAN]] Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact.<ref>PMID:17332497</ref> | [[http://www.uniprot.org/uniprot/MPP7_HUMAN MPP7_HUMAN]] Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact.<ref>PMID:17332497</ref> | ||
| - | + | == Evolutionary Conservation == | |
| - | == | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [[ | + | Check<jmol> |
| - | + | <jmolCheckbox> | |
| - | == | + | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o4/3o46_consurf.spt"</scriptWhenChecked> |
| - | <references | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | [[Category: | + | <text>to colour the structure by Evolutionary Conservation</text> |
| - | [[Category: Arrowsmith, C H | + | </jmolCheckbox> |
| - | [[Category: Bochkarev, A | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3o46 ConSurf]. |
| - | [[Category: Bountra, C | + | <div style="clear:both"></div> |
| - | [[Category: Edwards, A M | + | == References == |
| - | [[Category: Guan, X | + | <references/> |
| - | [[Category: Landry, R | + | __TOC__ |
| - | [[Category: Nedyalkova, L | + | </StructureSection> |
| - | [[Category: Park, H | + | [[Category: Human]] |
| - | [[Category: | + | [[Category: Arrowsmith, C H]] |
| - | [[Category: Tempel, W | + | [[Category: Bochkarev, A]] |
| - | [[Category: Tong, Y | + | [[Category: Bountra, C]] |
| - | [[Category: Weigelt, J | + | [[Category: Edwards, A M]] |
| - | [[Category: Zhong, N | + | [[Category: Guan, X]] |
| + | [[Category: Landry, R]] | ||
| + | [[Category: Nedyalkova, L]] | ||
| + | [[Category: Park, H]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Tempel, W]] | ||
| + | [[Category: Tong, Y]] | ||
| + | [[Category: Weigelt, J]] | ||
| + | [[Category: Zhong, N]] | ||
[[Category: Pdz domain]] | [[Category: Pdz domain]] | ||
[[Category: Protein binding]] | [[Category: Protein binding]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
| - | [[Category: Structural genomics consortium]] | ||
Current revision
Crystal structure of the PDZ domain of MPP7
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Categories: Human | Arrowsmith, C H | Bochkarev, A | Bountra, C | Edwards, A M | Guan, X | Landry, R | Nedyalkova, L | Park, H | Structural genomic | Tempel, W | Tong, Y | Weigelt, J | Zhong, N | Pdz domain | Protein binding | Sgc
