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3qio
From Proteopedia
(Difference between revisions)
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==Crystal Structure of HIV-1 RNase H with engineered E. coli loop and N-hydroxy quinazolinedione inhibitor== | ==Crystal Structure of HIV-1 RNase H with engineered E. coli loop and N-hydroxy quinazolinedione inhibitor== | ||
<StructureSection load='3qio' size='340' side='right' caption='[[3qio]], [[Resolution|resolution]] 1.40Å' scene=''> | <StructureSection load='3qio' size='340' side='right' caption='[[3qio]], [[Resolution|resolution]] 1.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3qio]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv- | + | <table><tr><td colspan='2'>[[3qio]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv-1 Hiv-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QIO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QIO FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=QID:3-HYDROXY-6-(PHENYLSULFONYL)QUINAZOLINE-2,4(1H,3H)-DIONE'>QID</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=QID:3-HYDROXY-6-(PHENYLSULFONYL)QUINAZOLINE-2,4(1H,3H)-DIONE'>QID</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3hyf|3hyf]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3hyf|3hyf]]</td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11706 HIV-1 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11706 HIV-1])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qio OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qio RCSB], [http://www.ebi.ac.uk/pdbsum/3qio PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qio OCA], [http://pdbe.org/3qio PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3qio RCSB], [http://www.ebi.ac.uk/pdbsum/3qio PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3qio ProSAT]</span></td></tr> |
</table> | </table> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 3qio" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Hiv-1 | + | [[Category: Hiv-1]] |
[[Category: Lansdon, E B]] | [[Category: Lansdon, E B]] | ||
[[Category: Liu, Q]] | [[Category: Liu, Q]] | ||
| - | [[Category: Hiv-1]] | ||
[[Category: Hydrolase-inhibitor complex]] | [[Category: Hydrolase-inhibitor complex]] | ||
[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
Revision as of 17:03, 5 August 2016
Crystal Structure of HIV-1 RNase H with engineered E. coli loop and N-hydroxy quinazolinedione inhibitor
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