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3o6d
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3o6d is ON HOLD Authors: Osipiuk, J., Zhou, M., Kwon, K., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSG...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Pyridoxal phosphate biosynthetic protein PdxJ from Campylobacter jejuni in complex with pyridoxine-5'-phosphate== | |
| - | + | <StructureSection load='3o6d' size='340' side='right' caption='[[3o6d]], [[Resolution|resolution]] 1.95Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3o6d]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Camje Camje]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O6D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3O6D FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=PXP:PYRIDOXINE-5-PHOSPHATE'>PXP</scene></td></tr> | |
| - | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3o6c|3o6c]]</td></tr> | |
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cj1238, pdxJ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=192222 CAMJE])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyridoxine_5'-phosphate_synthase Pyridoxine 5'-phosphate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.99.2 2.6.99.2] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o6d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o6d OCA], [http://pdbe.org/3o6d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3o6d RCSB], [http://www.ebi.ac.uk/pdbsum/3o6d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3o6d ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PDXJ_CAMJE PDXJ_CAMJE]] Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o6/3o6d_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3o6d ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Camje]] | ||
| + | [[Category: Pyridoxine 5'-phosphate synthase]] | ||
| + | [[Category: Anderson, W F]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Joachimiak, A]] | ||
| + | [[Category: Kwon, K]] | ||
| + | [[Category: Osipiuk, J]] | ||
| + | [[Category: Zhou, M]] | ||
| + | [[Category: Csgid]] | ||
| + | [[Category: Idp90671]] | ||
| + | [[Category: Pdxj]] | ||
| + | [[Category: Pyridoxal phosphate]] | ||
| + | [[Category: Pyridoxine synthesis]] | ||
| + | [[Category: Pyridoxine-5'-phosphate]] | ||
| + | [[Category: Transferase]] | ||
| + | [[Category: Vitamin b6]] | ||
Current revision
Pyridoxal phosphate biosynthetic protein PdxJ from Campylobacter jejuni in complex with pyridoxine-5'-phosphate
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