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4g2h

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==Structural basis for the accommodation of bis- and tris-aromatic derivatives in Vitamin D Nuclear Receptor==
==Structural basis for the accommodation of bis- and tris-aromatic derivatives in Vitamin D Nuclear Receptor==
<StructureSection load='4g2h' size='340' side='right' caption='[[4g2h]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='4g2h' size='340' side='right' caption='[[4g2h]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4g2h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Danio_rerio Danio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G2H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4G2H FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4g2h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Brachidanio_rerio Brachidanio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G2H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4G2H FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0VQ:(3E,5E)-6-(3-{2-[3,4-BIS(HYDROXYMETHYL)PHENYL]ETHYL}PHENYL)-1,1,1-TRIFLUORO-2-(TRIFLUOROMETHYL)OCTA-3,5-DIEN-2-OL'>0VQ</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0VQ:(3E,5E)-6-(3-{2-[3,4-BIS(HYDROXYMETHYL)PHENYL]ETHYL}PHENYL)-1,1,1-TRIFLUORO-2-(TRIFLUOROMETHYL)OCTA-3,5-DIEN-2-OL'>0VQ</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4g1d|4g1d]], [[4g1y|4g1y]], [[4g1z|4g1z]], [[4g20|4g20]], [[4g21|4g21]], [[4g2i|4g2i]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4g1d|4g1d]], [[4g1y|4g1y]], [[4g1z|4g1z]], [[4g20|4g20]], [[4g21|4g21]], [[4g2i|4g2i]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">vdra, nr1i1a, vdr ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7955 Danio rerio])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">vdra, nr1i1a, vdr ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7955 Brachidanio rerio])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_acetyltransferase Histone acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.48 2.3.1.48] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_acetyltransferase Histone acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.48 2.3.1.48] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4g2h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g2h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4g2h RCSB], [http://www.ebi.ac.uk/pdbsum/4g2h PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4g2h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g2h OCA], [http://pdbe.org/4g2h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4g2h RCSB], [http://www.ebi.ac.uk/pdbsum/4g2h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4g2h ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4g2h" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Danio rerio]]
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[[Category: Brachidanio rerio]]
[[Category: Histone acetyltransferase]]
[[Category: Histone acetyltransferase]]
[[Category: Ciesielski, F]]
[[Category: Ciesielski, F]]

Revision as of 22:49, 5 August 2016

Structural basis for the accommodation of bis- and tris-aromatic derivatives in Vitamin D Nuclear Receptor

4g2h, resolution 2.50Å

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