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Strictosidine Synthase
From Proteopedia
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== Structural highlights == | == Structural highlights == | ||
| - | The <scene name='10/100149/Cv/5'>substrate binding pocket of STR1 is located near the pseudo six-fold symmetry axis</scene><ref>PMID:16531499</ref>. | + | The <scene name='10/100149/Cv/5'>substrate binding pocket of STR1 is located near the pseudo six-fold symmetry axis</scene><ref>PMID:16531499</ref>. <scene name='10/100149/Cv/7'>Active site</scene>. Water molecule shown as red sphere. |
</StructureSection> | </StructureSection> | ||
==3D structures of strictosidine synthase== | ==3D structures of strictosidine synthase== | ||
Revision as of 11:08, 1 September 2016
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3D structures of strictosidine synthase
Updated on 01-September-2016
2fp8 – sSTR1 – serpentwood
3v1s – dSTR - devilpepper
2fp9 – sSTR1 + tartaric acid
2fpb – sSTR1 (mutant) + tryptamine
2fpc – sSTR1 + secologanin
2v91 – sSTR1 residues 32-333 + strictosidine
2vaq – sSTR1 + inhibitor
4imb, 4iyg – dSTR + indole derivative
References
- ↑ Stockigt J, Barleben L, Panjikar S, Loris EA. 3D-Structure and function of strictosidine synthase--the key enzyme of monoterpenoid indole alkaloid biosynthesis. Plant Physiol Biochem. 2008 Mar;46(3):340-55. doi: 10.1016/j.plaphy.2007.12.011. , Epub 2008 Jan 3. PMID:18280746 doi:http://dx.doi.org/10.1016/j.plaphy.2007.12.011
- ↑ Ma X, Panjikar S, Koepke J, Loris E, Stockigt J. The structure of Rauvolfia serpentina strictosidine synthase is a novel six-bladed beta-propeller fold in plant proteins. Plant Cell. 2006 Apr;18(4):907-20. Epub 2006 Mar 10. PMID:16531499 doi:10.1105/tpc.105.038018
