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5ix1
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of mouse Morc3 ATPase-CW cassette in complex with AMPPNP and H3K4me3 peptide== | |
| - | + | <StructureSection load='5ix1' size='340' side='right' caption='[[5ix1]], [[Resolution|resolution]] 2.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5ix1]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IX1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IX1 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene></td></tr> |
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ix2|5ix2]]</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ix1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ix1 OCA], [http://pdbe.org/5ix1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ix1 RCSB], [http://www.ebi.ac.uk/pdbsum/5ix1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ix1 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MORC3_MOUSE MORC3_MOUSE]] Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism (By similarity). Sumoylated MORC3-NBs can also associate with PML-NBs (By similarity). Recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity (PubMed:17332504). Binds RNA in vitro (By similarity).[UniProtKB:Q14149]<ref>PMID:17332504</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Du, J]] | ||
| + | [[Category: Li, S]] | ||
| + | [[Category: Patel, D J]] | ||
| + | [[Category: Atpase]] | ||
| + | [[Category: Cw domain]] | ||
| + | [[Category: H3k4me3]] | ||
| + | [[Category: Morc3]] | ||
| + | [[Category: Transcription]] | ||
Revision as of 00:04, 10 September 2016
Crystal structure of mouse Morc3 ATPase-CW cassette in complex with AMPPNP and H3K4me3 peptide
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Categories: Du, J | Li, S | Patel, D J | Atpase | Cw domain | H3k4me3 | Morc3 | Transcription
