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4z53

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'''Unreleased structure'''
 
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The entry 4z53 is ON HOLD until Paper Publication
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==Quinolone(Trovafloxacin)-DNA cleavage complex of topoisomerase IV from S. pneumoniae==
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<StructureSection load='4z53' size='340' side='right' caption='[[4z53]], [[Resolution|resolution]] 3.26&Aring;' scene=''>
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Authors: Laponogov, I., Veselkov, D.A., Pan, X.-S., Selvarajah, J., Crevel, I.M.-T., Fisher, L.M., Sanderson, M.R.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4z53]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z53 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Z53 FirstGlance]. <br>
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Description: Quinolone(Trovafloxacin)-DNA cleavage complex of topoisomerase IV from S. pneumoniae
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TR6:TROVAFLOXACIN'>TR6</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4koe|4koe]], [[4pxp|4pxp]], [[3rad|3rad]], [[3rae|3rae]], [[3raf|3raf]], [[3ksb|3ksb]], [[3ksa|3ksa]], [[4i3h|4i3h]]</td></tr>
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[[Category: Fisher, L.M]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4z53 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z53 OCA], [http://pdbe.org/4z53 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4z53 RCSB], [http://www.ebi.ac.uk/pdbsum/4z53 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4z53 ProSAT]</span></td></tr>
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[[Category: Pan, X.-S]]
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</table>
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[[Category: Sanderson, M.R]]
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== Function ==
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[[http://www.uniprot.org/uniprot/PARE_STRPN PARE_STRPN]] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.<ref>PMID:17375187</ref> <ref>PMID:20596531</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Crevel, I M.T]]
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[[Category: Fisher, L M]]
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[[Category: Laponogov, I]]
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[[Category: Pan, X S]]
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[[Category: Sanderson, M R]]
[[Category: Selvarajah, J]]
[[Category: Selvarajah, J]]
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[[Category: Veselkov, D.A]]
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[[Category: Veselkov, D A]]
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[[Category: Laponogov, I]]
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[[Category: Cleavage complex]]
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[[Category: Crevel, I.M.-T]]
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[[Category: Dna]]
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[[Category: Isomerase]]
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[[Category: Quinolone]]
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[[Category: Topo iv]]

Revision as of 15:25, 14 September 2016

Quinolone(Trovafloxacin)-DNA cleavage complex of topoisomerase IV from S. pneumoniae

4z53, resolution 3.26Å

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