5dnm
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Nucleosome core particle containing adducts of ruthenium(II)-toluene PTA complex== | |
| - | + | <StructureSection load='5dnm' size='340' side='right' caption='[[5dnm]], [[Resolution|resolution]] 2.81Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5dnm]] is a 10 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DNM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DNM FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RAX:DICHLORO[(1,2,3,4,5,6-ETA)-6-METHYLBENZENE]1,3,5-TRIAZA-7LAMBDA~5~-PHOSPHATRICYCLO[3.3.1.1~3,7~]DEC-7-YLRUTHENIUM'>RAX</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5dnn|5dnn]]</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dnm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dnm OCA], [http://pdbe.org/5dnm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dnm RCSB], [http://www.ebi.ac.uk/pdbsum/5dnm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dnm ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/H2B11_XENLA H2B11_XENLA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [[http://www.uniprot.org/uniprot/H32_XENLA H32_XENLA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [[http://www.uniprot.org/uniprot/H4_XENLA H4_XENLA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Adhireksan, Z]] | ||
| + | [[Category: Davey, C A]] | ||
| + | [[Category: Muhammad, R]] | ||
| + | [[Category: Histone binding]] | ||
| + | [[Category: Nucleosome]] | ||
| + | [[Category: Ruthenium antitumour compound]] | ||
| + | [[Category: Structural protein-dna complex]] | ||
Revision as of 15:29, 14 September 2016
Nucleosome core particle containing adducts of ruthenium(II)-toluene PTA complex
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