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5e8q
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of DHFR in 20% Isopropanol== | |
| - | + | <StructureSection load='5e8q' size='340' side='right' caption='[[5e8q]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5e8q]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E8Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5E8Q FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FOL:FOLIC+ACID'>FOL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5eaj|5eaj]]</td></tr> |
| - | [[Category: Agarwal, P | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] </span></td></tr> |
| - | [[Category: Cuneo, M | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5e8q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e8q OCA], [http://pdbe.org/5e8q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5e8q RCSB], [http://www.ebi.ac.uk/pdbsum/5e8q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5e8q ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/C3TR70_ECOLX C3TR70_ECOLX]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).[PIRNR:PIRNR000194] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Dihydrofolate reductase]] | ||
| + | [[Category: Agarwal, P K]] | ||
| + | [[Category: Cuneo, M J]] | ||
| + | [[Category: Dynamic]] | ||
| + | [[Category: Oxidoreductase]] | ||
Revision as of 13:48, 21 September 2016
Crystal structure of DHFR in 20% Isopropanol
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