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Trehalulose synthase

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== Function ==
== Function ==
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'''Trehalulose synthase''' (THS) converts sucrose to trehalulose (TH).
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'''Trehalulose synthase''' (THS) converts sucrose to trehalulose (TH)<ref>PMID:7878741</ref>.
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== Disease ==
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== Relevance ==
== Relevance ==
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== Structural highlights ==
== Structural highlights ==
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THS binds sucrose in a deep pocket with mostly conserved residues<ref>PMID:17597061</ref>.
</StructureSection>
</StructureSection>

Revision as of 08:53, 22 September 2016

Structure of trehalulose synthase complex with sucrose (stick model) and Ca+2 ion (green) (PDB code 2pwe).

Drag the structure with the mouse to rotate

3D structures of trehalulose synthase

Updated on 22-September-2016

References

  1. Thevelein JM, Hohmann S. Trehalose synthase: guard to the gate of glycolysis in yeast? Trends Biochem Sci. 1995 Jan;20(1):3-10. PMID:7878741
  2. Ravaud S, Robert X, Watzlawick H, Haser R, Mattes R, Aghajari N. Trehalulose synthase native and carbohydrate complexed structures provide insights into sucrose isomerization. J Biol Chem. 2007 Sep 21;282(38):28126-36. Epub 2007 Jun 27. PMID:17597061 doi:10.1074/jbc.M704515200

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Michal Harel, Alexander Berchansky

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