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Tumor necrosis factor receptor
From Proteopedia
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== Function == | == Function == | ||
| - | '''Tumor necrosis factor receptor''' (TNFR) or '''death receptor''' is a trimeric cytokine receptor which binds TNF. TNFR family contains several members and superfamily (TNFRSF) members. The extracellular domain of TNFR contains 2 to 6 cysteine-rich domains.<br /> | + | '''Tumor necrosis factor receptor''' (TNFR) or '''death receptor''' is a trimeric cytokine receptor which binds TNF<ref>PMID:10358762</ref>. TNFR family contains several members and superfamily (TNFRSF) members. The extracellular domain of TNFR contains 2 to 6 cysteine-rich domains.<br /> |
* '''TNFRSF 1''' is called '''Lymphotoxin-α or TNF-β''';<br /> | * '''TNFRSF 1''' is called '''Lymphotoxin-α or TNF-β''';<br /> | ||
* '''TNFRSF 3''' is called '''TNFR-III''';<br /> | * '''TNFRSF 3''' is called '''TNFR-III''';<br /> | ||
Revision as of 08:51, 28 September 2016
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3D structures of tumor necrosis factor receptor
Updated on 28-September-2016
References
- ↑ Wallach D, Varfolomeev EE, Malinin NL, Goltsev YV, Kovalenko AV, Boldin MP. Tumor necrosis factor receptor and Fas signaling mechanisms. Annu Rev Immunol. 1999;17:331-67. PMID:10358762 doi:http://dx.doi.org/10.1146/annurev.immunol.17.1.331
