7,8-dihydro-8-oxoguanine triphosphatase
From Proteopedia
(Difference between revisions)
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**[[3q93]], [[3zr1]] – hMTH1 - human <br /> | **[[3q93]], [[3zr1]] – hMTH1 - human <br /> | ||
**[[1iry]] – hMTH1 - NMR<br /> | **[[1iry]] – hMTH1 - NMR<br /> | ||
| - | **[[3zr0]] – hMTH1 + | + | **[[5fsi]], [[5fsk]], [[3zr0]] – hMTH1 + 8-oxo-DGTP<br /> |
| - | **[[3whw]], [[4n1t]], [[4n1u]] – hMTH1 + inhibitor<br /> | + | **[[5fsl]], [[5fsm]], [[5fsn]] – hMTH1 + substrate analog<br /> |
| - | **[[4c9w]], [[4c9x]] | + | **[[3whw]], [[4n1t]], [[4n1u]], [[3whw]] – hMTH1 + inhibitor<br /> |
| + | **[[4c9w]], [[4c9x]], [[5ans]], [[5ant]], [[5anu]], [[5anw]], [[5anu]], [[4n1t]], [[4n1u]], [[4c9w]], [[4c9x]] - hMTH1 + anti-cancer drug<br /> | ||
}} | }} | ||
Revision as of 20:17, 31 October 2016
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3D structures of 7,8-dihydro-8-oxoguanine triphosphatase
Updated on 31-October-2016
References
- ↑ Nakamura T, Meshitsuka S, Kitagawa S, Abe N, Yamada J, Ishino T, Nakano H, Tsuzuki T, Doi T, Kobayashi Y, Fujii S, Sekiguchi M, Yamagata Y. Structural and dynamic features of the MutT protein in the recognition of nucleotides with the mutagenic 8-oxoguanine base. J Biol Chem. 2010 Jan 1;285(1):444-52. Epub 2009 Oct 28. PMID:19864691 doi:10.1074/jbc.M109.066373
- ↑ Svensson LM, Jemth AS, Desroses M, Loseva O, Helleday T, Hogbom M, Stenmark P. Crystal structure of human MTH1 and the 8-oxo-dGMP product complex. FEBS Lett. 2011 Aug 19;585(16):2617-21. Epub 2011 Jul 23. PMID:21787772 doi:10.1016/j.febslet.2011.07.017
