3p1m
From Proteopedia
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==Crystal structure of human ferredoxin-1 (FDX1) in complex with iron-sulfur cluster== | ==Crystal structure of human ferredoxin-1 (FDX1) in complex with iron-sulfur cluster== | ||
<StructureSection load='3p1m' size='340' side='right' caption='[[3p1m]], [[Resolution|resolution]] 2.54Å' scene=''> | <StructureSection load='3p1m' size='340' side='right' caption='[[3p1m]], [[Resolution|resolution]] 2.54Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3p1m]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3p1m]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P1M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3P1M FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ADX, FDX1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ADX, FDX1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3p1m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p1m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3p1m RCSB], [http://www.ebi.ac.uk/pdbsum/3p1m PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3p1m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p1m OCA], [http://pdbe.org/3p1m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3p1m RCSB], [http://www.ebi.ac.uk/pdbsum/3p1m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3p1m ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ADX_HUMAN ADX_HUMAN]] Participates in the synthesis of thyroid hormones. Essential for the synthesis of various steroid hormones, participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage.<ref>PMID:20547883</ref> <ref>PMID:21636783</ref> | ||
==See Also== | ==See Also== | ||
*[[Ferredoxin|Ferredoxin]] | *[[Ferredoxin|Ferredoxin]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Arrowsmith, C H]] | [[Category: Arrowsmith, C H]] | ||
[[Category: Bountra, C]] | [[Category: Bountra, C]] | ||
Revision as of 03:52, 10 December 2016
Crystal structure of human ferredoxin-1 (FDX1) in complex with iron-sulfur cluster
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Categories: Human | Arrowsmith, C H | Bountra, C | Bray, J E | Chaikuad, A | Edwards, A M | Johansson, C | Kavanagh, K | Krojer, T | Muniz, J R.C | Oppermann, U | Phillips, C | Pike, A C.W | Structural genomic | Vollmar, M | Weigelt, J | Yue, W W | Adrenodoxin | Electron transport | Ferredoxin | Iron-sulfur cluster | Mitochondria | Sgc
