This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3nck
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| + | |||
==Crystal Structure of BlaC-E166A covalently bound with Nafcillin== | ==Crystal Structure of BlaC-E166A covalently bound with Nafcillin== | ||
<StructureSection load='3nck' size='340' side='right' caption='[[3nck]], [[Resolution|resolution]] 2.80Å' scene=''> | <StructureSection load='3nck' size='340' side='right' caption='[[3nck]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3nck]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3nck]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NCK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NCK FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NFF:(2R,4S)-2-[(1R)-1-{[(2-ETHOXYNAPHTHALEN-1-YL)CARBONYL]AMINO}-2-OXOETHYL]-5,5-DIMETHYL-1,3-THIAZOLIDINE-4-CARBOXYLIC+ACID'>NFF</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NFF:(2R,4S)-2-[(1R)-1-{[(2-ETHOXYNAPHTHALEN-1-YL)CARBONYL]AMINO}-2-OXOETHYL]-5,5-DIMETHYL-1,3-THIAZOLIDINE-4-CARBOXYLIC+ACID'>NFF</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">blaA, blaC, MT2128, MTCY49.07c, Rv2068c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">blaA, blaC, MT2128, MTCY49.07c, Rv2068c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr> |
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nck FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nck OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nck RCSB], [http://www.ebi.ac.uk/pdbsum/3nck PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nck FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nck OCA], [http://pdbe.org/3nck PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3nck RCSB], [http://www.ebi.ac.uk/pdbsum/3nck PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3nck ProSAT]</span></td></tr> |
</table> | </table> | ||
| Line 14: | Line 15: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Beta-lactamase]] | [[Category: Beta-lactamase]] | ||
| - | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Blanchard, J S]] | [[Category: Blanchard, J S]] | ||
[[Category: Tremblay, L W]] | [[Category: Tremblay, L W]] | ||
Revision as of 03:53, 10 December 2016
Crystal Structure of BlaC-E166A covalently bound with Nafcillin
| |||||||||||
