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5eu9
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of Human Enolase 2 in complex with ((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonic acid== | |
| - | + | <StructureSection load='5eu9' size='340' side='right' caption='[[5eu9]], [[Resolution|resolution]] 2.05Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5eu9]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EU9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EU9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5TX:((3S,5S)-1,5-DIHYDROXY-3-METHYL-2-OXOPYRROLIDIN-3-YL)PHOSPHONIC+ACID'>5TX</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zcw|4zcw]], [[4za0|4za0]], [[1te6|1te6]], [[2akm|2akm]], [[2akz|2akz]], [[3ucc|3ucc]], [[3ucd|3ucd]], [[3uje|3uje]], [[3ujf|3ujf]], [[3ujr|3ujr]], [[3ujs|3ujs]]</td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphopyruvate_hydratase Phosphopyruvate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.11 4.2.1.11] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5eu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eu9 OCA], [http://pdbe.org/5eu9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5eu9 RCSB], [http://www.ebi.ac.uk/pdbsum/5eu9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5eu9 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ENOG_HUMAN ENOG_HUMAN]] Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Phosphopyruvate hydratase]] | ||
| + | [[Category: Leonard, P G]] | ||
| + | [[Category: Muller, F L]] | ||
| + | [[Category: Carbohydrate metabolism]] | ||
| + | [[Category: Enolase gamma]] | ||
| + | [[Category: Glycolysis]] | ||
| + | [[Category: Lyase-lyase inhibitor complex]] | ||
| + | [[Category: Neuron specific enolase]] | ||
Revision as of 10:49, 10 December 2016
Structure of Human Enolase 2 in complex with ((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonic acid
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