5ko2

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'''Unreleased structure'''
 
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The entry 5ko2 is ON HOLD until Paper Publication
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==Mouse pgp 34 linker deleted mutant Hg derivative==
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<StructureSection load='5ko2' size='340' side='right' caption='[[5ko2]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
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Authors: Xia, D., Esser, L., Zhou, F.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5ko2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KO2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KO2 FirstGlance]. <br>
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Description: Mouse pgp 34 linker deleted mutant Hg derivative
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5kpd|5kpd]], [[5koy|5koy]], [[5kpj|5kpj]], [[5kpi|5kpi]]</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Xenobiotic-transporting_ATPase Xenobiotic-transporting ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.44 3.6.3.44] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ko2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ko2 OCA], [http://pdbe.org/5ko2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ko2 RCSB], [http://www.ebi.ac.uk/pdbsum/5ko2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ko2 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/MDR1A_MOUSE MDR1A_MOUSE]] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.<ref>PMID:19325113</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Xenobiotic-transporting ATPase]]
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[[Category: Esser, L]]
[[Category: Xia, D]]
[[Category: Xia, D]]
[[Category: Zhou, F]]
[[Category: Zhou, F]]
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[[Category: Esser, L]]
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[[Category: Drug transport]]
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[[Category: Hydrolase]]
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[[Category: Mercury derivative]]
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[[Category: Mouse pgp]]
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[[Category: Multidrug resistance]]

Revision as of 18:35, 10 December 2016

Mouse pgp 34 linker deleted mutant Hg derivative

5ko2, resolution 3.30Å

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