5k7x

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'''Unreleased structure'''
 
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The entry 5k7x is ON HOLD until Nov 27 2017
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==Fully ligated Adenylosuccinate Synthetase from Pyrococcus horikoshii OT3 with GTP, IMP and Hadacidin==
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<StructureSection load='5k7x' size='340' side='right' caption='[[5k7x]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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Authors: Xie, Y., Cheng, Z.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5k7x]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K7X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5K7X FirstGlance]. <br>
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Description: Fully ligated Adenylosuccinate Synthetase from Pyrococcus horikoshii OT3 with GTP, IMP and Hadacidin
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=HDA:HADACIDIN'>HDA</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2d7u|2d7u]]</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenylosuccinate_synthase Adenylosuccinate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.4 6.3.4.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5k7x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k7x OCA], [http://pdbe.org/5k7x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5k7x RCSB], [http://www.ebi.ac.uk/pdbsum/5k7x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5k7x ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PURA_PYRHO PURA_PYRHO]] Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
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__TOC__
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</StructureSection>
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[[Category: Adenylosuccinate synthase]]
[[Category: Cheng, Z]]
[[Category: Cheng, Z]]
[[Category: Xie, Y]]
[[Category: Xie, Y]]
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[[Category: Adenylosuccinate synthetase]]
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[[Category: Gtp]]
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[[Category: Hadacidin]]
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[[Category: Imp]]
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[[Category: Ligase]]
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[[Category: Pyrococcus horikoshii ot3]]

Revision as of 02:15, 11 December 2016

Fully ligated Adenylosuccinate Synthetase from Pyrococcus horikoshii OT3 with GTP, IMP and Hadacidin

5k7x, resolution 2.80Å

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