Folylpolyglutamate synthase

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(New page: <StructureSection load='2vor' size='340' side='right' caption='Folypolyglutamate synthase complex with ADP and AMPPCP (PDB code 2vor' scene=''> == Function == '''Folypolyglutamate s...)
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<StructureSection load='2vor' size='340' side='right' caption='Folypolyglutamate synthase complex with ADP, AMPPCP and Co+2 ion (pink) (PDB code [[2vor]]' scene=''>
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<StructureSection load='2vor' size='340' side='right' caption='Folypolyglutamate synthase complex with ADP and AMPPCP (PDB code [[2vor]]' scene=''>
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
*Folypolyglutamate synthase
*Folypolyglutamate synthase
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**[[1jbw]] – LcFPGS + AMPPCP + folate derivative <BR />
**[[1jbw]] – LcFPGS + AMPPCP + folate derivative <BR />
**[[1fgs]] – LcFPGS + pyrophosphate <BR />
**[[1fgs]] – LcFPGS + pyrophosphate <BR />
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== References ==
== References ==
<references/>
<references/>

Revision as of 11:01, 15 December 2016

Folypolyglutamate synthase complex with ADP, AMPPCP and Co+2 ion (pink) (PDB code 2vor

Drag the structure with the mouse to rotate

3D structures of folypolyglutamate synthase

Updated on 15-December-2016

References

  1. Kim SE, Hinoue T, Kim MS, Sohn KJ, Cho RC, Weisenberger DJ, Laird PW, Kim YI. Effects of folylpolyglutamate synthase modulation on global and gene-specific DNA methylation and gene expression in human colon and breast cancer cells. J Nutr Biochem. 2016 Mar;29:27-35. doi: 10.1016/j.jnutbio.2015.10.019. Epub 2015 , Nov 17. PMID:26895662 doi:http://dx.doi.org/10.1016/j.jnutbio.2015.10.019
  2. Sohn KJ, Smirnakis F, Moskovitz DN, Novakovic P, Yates Z, Lucock M, Croxford R, Kim YI. Effects of folylpolyglutamate synthetase modulation on chemosensitivity of colon cancer cells to 5-fluorouracil and methotrexate. Gut. 2004 Dec;53(12):1825-31. PMID:15542523 doi:http://dx.doi.org/10.1136/gut.2004.042713
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