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5gjh

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'''Unreleased structure'''
 
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The entry 5gjh is ON HOLD until Paper Publication
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==Gads SH2 domain/CD28-derived peptide complex==
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<StructureSection load='5gjh' size='340' side='right' caption='[[5gjh]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
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Authors: Inaba, S., Numoto, N., Morii, H., Ogawa, S., Ikura, T., Abe, R., Ito, N., Oda, M.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5gjh]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GJH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GJH FirstGlance]. <br>
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Description: Gads SH2 domain/CD28-derived peptide complex
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5gji|5gji]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5gjh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gjh OCA], [http://pdbe.org/5gjh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gjh RCSB], [http://www.ebi.ac.uk/pdbsum/5gjh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gjh ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/GRAP2_HUMAN GRAP2_HUMAN]] Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc. [[http://www.uniprot.org/uniprot/CD28_HUMAN CD28_HUMAN]] Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.
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__TOC__
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</StructureSection>
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[[Category: Abe, R]]
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[[Category: Ikura, T]]
[[Category: Inaba, S]]
[[Category: Inaba, S]]
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[[Category: Ito, N]]
[[Category: Morii, H]]
[[Category: Morii, H]]
[[Category: Numoto, N]]
[[Category: Numoto, N]]
[[Category: Oda, M]]
[[Category: Oda, M]]
[[Category: Ogawa, S]]
[[Category: Ogawa, S]]
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[[Category: Ito, N]]
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[[Category: Antigen]]
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[[Category: Ikura, T]]
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[[Category: Phosphopeptide]]
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[[Category: Abe, R]]
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[[Category: Signaling protein]]

Revision as of 19:15, 15 December 2016

Gads SH2 domain/CD28-derived peptide complex

5gjh, resolution 1.20Å

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