4hsg
From Proteopedia
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==Crystal structure of human PRMT3 in complex with an allosteric inhibitor (PRMT3- KTD)== | ==Crystal structure of human PRMT3 in complex with an allosteric inhibitor (PRMT3- KTD)== | ||
<StructureSection load='4hsg' size='340' side='right' caption='[[4hsg]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='4hsg' size='340' side='right' caption='[[4hsg]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4hsg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[4hsg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HSG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HSG FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KTD:1-(1,2,3-BENZOTHIADIAZOL-6-YL)-3-(2-OXO-2-PHENYLETHYL)UREA'>KTD</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KTD:1-(1,2,3-BENZOTHIADIAZOL-6-YL)-3-(2-OXO-2-PHENYLETHYL)UREA'>KTD</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PRMT3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PRMT3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hsg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hsg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hsg RCSB], [http://www.ebi.ac.uk/pdbsum/4hsg PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hsg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hsg OCA], [http://pdbe.org/4hsg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hsg RCSB], [http://www.ebi.ac.uk/pdbsum/4hsg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hsg ProSAT]</span></td></tr> |
</table> | </table> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Arrowsmith, C H]] | [[Category: Arrowsmith, C H]] | ||
[[Category: Bountra, C]] | [[Category: Bountra, C]] | ||
Revision as of 07:13, 23 December 2016
Crystal structure of human PRMT3 in complex with an allosteric inhibitor (PRMT3- KTD)
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Categories: Human | Arrowsmith, C H | Bountra, C | Brown, P J | Dobrovetsky, E | Dong, A | Edwards, A M | Hajian, T | Jin, J | Li, F | Liu, F | Structural genomic | Schapira, M | Siarheyeva, A | Smil, D | Tempel, W | Vedadi, M | Allosteric inhibitor | Prmt3 | Sgc | Transferase-transferase inhibitor complex
